نتایج جستجو برای: chromosorb 102

تعداد نتایج: 24460  

Journal: :Journal of Physics: Conference Series 2014

Journal: :Annals of Oncology 2023

In metastatic colorectal cancer (mCRC) the choice of treatment should take into account characteristics tumor and patient, as well its efficacy tolerability. The RECOURSE study demonstrated that presence low burden indolent disease has an impact on progression-free (PFS) overall (OS) survival patients treated with trifluridine/tipiracil (TAS-102). Retrospective included mCRC undergoing TAS-102 ...

Journal: :Human Reproduction 2023

Abstract Study question Which add-ons are effective and safe to use in the ART clinic? Summary answer More than thirty recommendations were formulated on of diagnosis diagnostic tests, laboratory tests intervention, clinical management. What is known already Treatment not essential for treatment but optional additional treatments that sometimes offered top routine fertility treatment. There a w...

Journal: :European journal of risk regulation 2023

Abstract High pharmaceutical pricing practices in Europe have been increasingly on the radar of European Union, academia and civil society as a risk to Member State health budgets. It is therefore hardly surprising that, recent years, competition authorities resuscitated excessive prohibition contained Article 102(a) TFEU. Focusing this phenomenon, piece highlights diverse ways which United Bra...

2000
DONNA-MARIE MCCAFFERTY ELAINE SIHOTA MARCELO MUSCARA JOHN L. WALLACE KEITH A. SHARKEY PAUL KUBES

McCafferty, Donna-Marie, Elaine Sihota, Marcelo Muscara, John L. Wallace, Keith A. Sharkey, and Paul Kubes. Spontaneously developing chronic colitis in IL-10/ iNOS double-deficient mice. Am J Physiol Gastrointest Liver Physiol 279: G90–G99, 2000.—Mice deficient in both inducible nitric oxide synthase (iNOS) and interleukin (IL)-10 (iNOS2/2/IL-102/2) were created to examine the role of iNOS in s...

2012
George B. Lenon C. G. Li C. Da Costa F. C. K. Thien Y. Shen C. C. L. Xue

BACKGROUND A herbal preparation, known as RMIT Chinese Medicine 102 (RCM-102) consisting of eight herbs which demonstrates inhibition of the release of key inflammatory mediators associated with seasonal allergic rhinitis (SAR) was used. This study evaluated the efficacy and safety of RCM-102 for SAR. OBJECTIVE This study evaluated the efficacy and safety of RCM-102 for SAR. METHODS This ra...

Journal: :The New England journal of medicine 2015
Robert J Mayer Eric Van Cutsem Alfredo Falcone Takayuki Yoshino Rocio Garcia-Carbonero Nobuyuki Mizunuma Kentaro Yamazaki Yasuhiro Shimada Josep Tabernero Yoshito Komatsu Alberto Sobrero Eveline Boucher Marc Peeters Ben Tran Heinz-Josef Lenz Alberto Zaniboni Howard Hochster James M Cleary Hans Prenen Fabio Benedetti Hirokazu Mizuguchi Lukas Makris Masanobu Ito Atsushi Ohtsu

BACKGROUND Early clinical trials conducted primarily in Japan have shown that TAS-102, an oral agent that combines trifluridine and tipiracil hydrochloride, was effective in the treatment of refractory colorectal cancer. We conducted a phase 3 trial to further assess the efficacy and safety of TAS-102 in a global population of such patients. METHODS In this double-blind study, we randomly ass...

2017
Vincenzo Sforza Erika Martinelli Claudia Cardone Giulia Martini Stefania Napolitano Pietro Paolo Vitiello Pasquale Vitale Nicoletta Zanaletti Alfonso Reginelli Maurizio Di Bisceglie Tiziana Pia Latiano Anna Maria Bochicchio Fabiana Cecere Francesco Selvaggi Fortunato Ciardiello Teresa Troiani

BACKGROUND TAS-102 improves overall survival (OS) in patients with metastatic colorectal cancer (mCRC) refractory to standard treatments. However, predictive biomarkers of efficacy are currently lacking. PATIENTS AND METHODS We treated a cohort of 43 chemorefractory mCRC patients treated with TAS-102, in a single institution expanded access, compassionate use programme. We stratified patients...

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