نتایج جستجو برای: chromophobe

تعداد نتایج: 576  

2016
Shigekatsu Maekawa Masayoshi Nagata Hiroshi Watanabe Keina Nozaki Atsuko Takahashi Shigeru Minowada Yukio Homma

Idiopathic thrombocytopenic purpura (ITP) associated with renal cell carcinoma (RCC) is relatively rare. In almost all of these case reports, patients affected with ITP developed differentially-involved cancer, because resection of cancer could not improve thrombocytopenia and the treatment of ITP needed to be continued after surgery. We report the case of a 48-year-old woman with massive renal...

Journal: :JCI insight 2017
Jozefina Casuscelli Nils Weinhold Gunes Gundem Lu Wang Emily C Zabor Esther Drill Patricia I Wang Gouri J Nanjangud Almedina Redzematovic Amrita M Nargund Brandon J Manley Maria E Arcila Nicholas M Donin John C Cheville R Houston Thompson Allan J Pantuck Paul Russo Emily H Cheng William Lee Satish K Tickoo Irina Ostrovnaya Chad J Creighton Elli Papaemmanuil Venkatraman E Seshan A Ari Hakimi James J Hsieh

Chromophobe renal cell carcinoma (chRCC) typically shows ~7 chromosome losses (1, 2, 6, 10, 13, 17, and 21) and ~31 exonic somatic mutations, yet carries ~5%-10% metastatic incidence. Since extensive chromosomal losses can generate proteotoxic stress and compromise cellular proliferation, it is intriguing how chRCC, a tumor with extensive chromosome losses and a low number of somatic mutations,...

2014
Bengt Edvardsson

INTRODUCTION Cluster headache belongs to a group of primary headache entities: the trigeminal autonomic cephalalgias. Cluster headache is the most common variant. The headache is usually severe and it is also associated with autonomic symptoms. Secondary causes of cluster headache have been reported, such as intracranial artery aneurysms and tumors. The question of when to carry out neuroimagin...

2017
Junlong Wu Peipei Zhang Guiming Zhang Hongkai Wang Weijie Gu Bo Dai Hailiang Zhang Guohai Shi Yijun Shen Yiping Zhu Yao Zhu Dingwei Ye

The distribution pattern of renal cell carcinoma (RCC) histological subtypes according to age, gender and tumor size has not been well illustrated in RCC patients living in fast-developing regions of China. We recruited 2941 patients with clear cell renal cell carcinoma (ccRCC), papillary renal cell carcinoma (PCC) or chromophobe from two hospitals in coastal China (2004-2012) consecutively and...

2017
Xiang-hui Ning Yan-qing Gong Shi-ming He Teng Li Jiang-yi Wang Shuang-he Peng Jin-chao Chen Jia-yuan Liu Nie-nie Qi Ying-lu Guo Kan Gong

Renal cell carcinoma is one of the most common urological tumors. The role of programmed cell death 1 ligand 1 (PD-L1) in renal cell carcinomas in predicting outcome of the patients is yet unclear. We analyzed the clinical and RNA-seq data of 522 kidney clear cell cancer, 259 kidney papillary cell carcinoma and 66 kidney chromophobe patients from The Cancer Genome Atlas (TCGA) database. In kidn...

2014
Humera Shahzad Shahnaz Imdad Kehar Shahzad Ali Naila Tariq

OBJECTIVE To evaluate the expression of Von Hippel Lindau (VHL) gene in diagnosed cases of renal cell carcinoma. METHODS This cross sectional study was conducted in department of Pathology, Basic Medical Sciences Institute, JPMC, Karachi, from January 2007 to December 2012. Paraffin embedded blocks of 30 cases of radical nephrectomy specimens diagnosed as renal cell carcinoma including CCRCC ...

2017
Rileen Sinha Andrew G Winer Michael Chevinsky Christopher Jakubowski Ying-Bei Chen Yiyu Dong Satish K Tickoo Victor E Reuter Paul Russo Jonathan A Coleman Chris Sander James J Hsieh A Ari Hakimi

The utility of cancer cell lines is affected by the similarity to endogenous tumour cells. Here we compare genomic data from 65 kidney-derived cell lines from the Cancer Cell Line Encyclopedia and the COSMIC Cell Lines Project to three renal cancer subtypes from The Cancer Genome Atlas: clear cell renal cell carcinoma (ccRCC, also known as kidney renal clear cell carcinoma), papillary (pRCC, al...

Journal: :Journal of Veterinary Diagnostic Investigation 2010

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