نتایج جستجو برای: chordin

تعداد نتایج: 380  

Journal: :Mechanisms of Development 2008
Susumu Matsushita Koko Urase Akira Komatsu Paul J. Scotting Atsushi Kuroiwa Sadao Yasugi

In this study, the initial specification of foregut endoderm in the chick embryo was analyzed. A fate map constructed for the area pellucida endoderm at definitive streak-stage showed centrally-located presumptive cells of foregut-derived organs around Hensen's node. Intracoelomic cultivation of the area pellucida endoderm at this stage combined with somatic mesoderm resulted in the differentia...

Journal: :Annual review of cell and developmental biology 2004
Edward M De Robertis Hiroki Kuroda

We review the current status of research in dorsal-ventral (D-V) patterning in vertebrates. Emphasis is placed on recent work on Xenopus, which provides a paradigm for vertebrate development based on a rich heritage of experimental embryology. D-V patterning starts much earlier than previously thought, under the influence of a dorsal nuclear -Catenin signal. At mid-blastula two signaling center...

Journal: :Mechanisms of Development 2004
Hideaki Nojima Takashi Shimizu Cheol-Hee Kim Taijiro Yabe Young-Ki Bae Osamu Muraoka Tsutomu Hirata Ajay Chitnis Toshio Hirano Masahiko Hibi

In zebrafish, the program for dorsal specification begins soon after fertilization. Dorsal determinants are localized initially to the vegetal pole, then transported to the blastoderm, where they are thought to activate the canonical Wnt pathway, which induces the expression of dorsal-specific genes. We identified a novel maternal-effect recessive mutation, tokkaebi (tkk), that affects formatio...

Journal: :Development 2005
Thomas P Wilm Lilianna Solnica-Krezel

During vertebrate development the dorsal gastrula or Spemann-Mangold organizer orchestrates axis formation largely by limiting the ventralizing and posteriorizing activity of bone morphogenetic proteins (BMPs). In mouse and Xenopus laevis, genes encoding the zinc finger transcriptional repressor Prdm1/Blimp1 (PR domain containing 1, with ZNF domain; previously named B lymphocyte-induced maturat...

2010
Hye-Joo Kwon Neha Bhat Elly M. Sweet Robert A. Cornell Bruce B. Riley

Preplacodal ectoderm arises near the end of gastrulation as a narrow band of cells surrounding the anterior neural plate. This domain later resolves into discrete cranial placodes that, together with neural crest, produce paired sensory structures of the head. Unlike the better-characterized neural crest, little is known about early regulation of preplacodal development. Classical models of ect...

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