A number of antipsychotic drugs have been available in the US, beginning in the early 1950s with chlorpromazine, and these drugs have proven to be immensely useful in the treatment of various psychotic illnesses, in particular schizophrenia. Several of these drugs are available in parenteral form, e.g., haloperidol and chlorpromazine, for intramuscular (IM) use. Many clinicians have found these...

The concentrations of 11 amino acids were determined in 9 regions of the rat brain following the acute administration of the antidepressant drugs imipramine and Org. GB94, and chlorpromazine. The amino acids were determined as their dansyl derivatives. Unequivocal changes were only found in the concentrations of gamma-aminobutyric acid, alanine, asparagine + glutamine, glycine and taurine in so...