نتایج جستجو برای: chlorpheniramine

تعداد نتایج: 672  

Journal: :Journal of pharmaceutical sciences 2004
Marina Levina Ali R Rajabi-Siahboomi

The influence of commonly used excipients, spray-dried lactose (SDL), microcrystalline cellulose (MCC), and partially pregelatinized maize starch (Starch 1500) on drug release from hydroxypropyl methylcellulose (HPMC, hypromellose) matrix system has been investigated. A model formulation contained 30%w/w drug, 20%w/w HPMC, 0.5%w/w fumed silica, 0.25%w/w magnesium stearate, and 49.25%w/w filler....

Journal: :Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005
B Olmo A García A Marín C Barbas

The development of new pharmaceutical forms with classical active compounds generates new analytical problems. That is the case of sugar-free sachets of cough-cold products containing acetaminophen, phenylephrine hydrochloride and chlorpheniramine maleate. Two cyanopropyl stationary phases have been employed to tackle the problem. The Discovery cyanopropyl (SUPELCO) column permitted the separat...

Journal: :Chemical & pharmaceutical bulletin 2014
Keiichi Motoyama Yuki Tanida Kyona Hata Tomoya Hayashi Taishi Higashi Yoichi Ishitsuka Yuki Kondo Tetsumi Irie Shinichiro Kaneko Hidetoshi Arima

A megamolecular polysaccharide sacran was newly extracted from cyanobacterium Aphanothece sacrum. Sacran has many preferable properties for transdermal application, e.g. a safe biomaterial, a high moisturizing effect, a formation of film and hydrogel. Additionally, it was recently discovered that sacran has an anti-inflammatory effect for atopic dermatitis model mice. In this study, in order to...

Journal: :Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 2010
I Murat Palabiyik Feyyaz Onur

A fast, accurate, precise and sensitive capillary electrophoresis method for the simultaneous determination of dextromethorphan hydrobromide, phenylephrine hydrochloride, paracetamol and chlorpheniramine maleate has been developed. Response surface methodology with a central composite design was used for optimization of the concentration of the buffer, pH of the buffer and applied voltage. Ther...

2008
A. U. Kadam D. M. Sakarkar P. S. Kawtikwar

An oral controlled release suspension of chlorpheniramine maleate was prepared using ion-exchange resin technology. A strong cation exchange resin Indion 244 was utilized for the sorption of the drug and the drug resinates was evaluated for various physical and chemical parameters. The drug-resinate complex was microencapsulated with a polymer Eudragit RS 100 to further retard the release chara...

Journal: :Journal of controlled release : official journal of the Controlled Release Society 2006
Mamoru Fukuda Nicholas A Peppas James W McGinity

The purpose of this study was to investigate the influence of sodium bicarbonate on the physicochemical properties of controlled release hot-melt extruded (HME) tablets containing Eudragit RS PO and/or Eudragit E PO. Acetohydroxamic acid and chlorpheniramine maleate were used as model drugs. Sodium bicarbonate was incorporated into the tablet formulations and the drug release properties and buo...

Journal: :The Journal of the Association of Physicians of India 2014
Nasim Zamani

*Department of Clinical Toxicology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Received: 09.08.2012; Accepted: 08.02.2014 Sir, I read with interest the case presented by Rajendiran C et al . enti t led:” Stroke after multiple bee sting” recently published in J Assoc Physicians India.1 The authors have presented a 25-yearold male referring to them after ...

2011
Antonin Lojek Milan Číž Michaela Pekarová Gabriela Ambrožová Ondřej Vašíček Jana Moravcová Lukáš Kubala Katarína Drábiková Viera Jančinová Tomáš Perečko Jana Pečivová Tatiana Mačičková Radomír Nosál

The purpose of the study was to investigate the effects of H(1)-antihistamines of the 1(st) generation (antazoline, bromadryl, brompheniramine, dithiaden, cyclizine, chlorcyclizine, chlorpheniramine, clemastine) and the 2(nd) generation (acrivastine, ketotifen, and loratadine) on the respiratory burst of phagocytes. Reactive oxygen species generation in neutrophils isolated from rat blood was m...

Journal: :Neuroendocrinology 2013
Megumi Ikegami Hiroko Ikeda Takahiro Ohashi Misa Kai Mamiko Osada Atsuko Kamei Junzo Kamei

BACKGROUND/AIMS Atypical antipsychotic drugs such as olanzapine are known to induce metabolic disturbance. We have already shown that olanzapine induces hepatic glucose production through the activation of hypothalamic adenosine 5'-monophosphate-activated protein kinase (AMPK). However, it is unclear how olanzapine activates hypothalamic AMPK. Since olanzapine is known to antagonize several rec...

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