Abstract Oxidation is a prominent degradation route of biological molecules that produces wide variety products through complex mechanisms and hence qualifies to be vital pharmaceutical process. This article presents the kinetic spectral study oxidation an antimigraine drug rizatriptan benzoate (RTB) in acid medium with aid mild biocidal oxidant N -chloro- p -toluenesulfonamide, referred as chl...

The known drawbacks of chloramination include nitrification, elastomer decay, and required pretreatment steps for fish culture and dialysis patients. To date, there has been no explicit consideration of adverse consequences of chloramination on property and water quality in buildings. Specifically, the effect of chloramine on re-growth of bacteria during stagnation, plumbing failures and lead l...

Activated phagocytes produce the highly reactive oxidant hypochlorous acid (HOCl) via the myeloperoxidase-catalysed reaction of hydrogen peroxide with chloride ions. HOCl reacts readily with a number of susceptible targets on apolipoprotein B-100 of low-density lipoprotein (LDL), resulting in uncontrolled uptake of HOCl-modified LDL by macrophages. We have investigated the effects of vitamin C ...

1. Dakin's hypochlorite solution has the power of dissolving necrotic tissue, pus, and plasma clot in the concentration and reaction used clinically. 2. Chloramine-T and dichloramine-T do not exhibit this action. 3. The solvent action of Dakin's hypochlorite solution of the degree of alkalinity used clinically is due primarily to its hypochlorite content, but its slight alkalinity, while in its...