Radiation is one of the most widespread sources of environmental stress in living environment which cause oxidative stress and metabolic changes. Chitosan is widely distributed in nature as a component of bacterial cell walls and exoskeletons of crustaceans and insects. The present study aims to evaluate the antioxidant effect of chitosan against gamma rays induced oxidative stress and metaboli...

OBJECTIVE Maternal glycemia plays a key role in fetal growth. We hypothesized that lower glycemic load (GL) meals (lower glycemic index, modestly lower carbohydrate) would substantially reduce day-long glucose variability in women at risk of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS A crossover study of 17 women (mean±SD age 34.8±4 years; gestational weeks 29.3±1.3; bod...

Gamma (gamma)-irradiation is finding increasing use in the sterilization of pharmaceutical products. However, irradiation also might affect the performance of drug delivery systems. In this study, the influence of gamma-irradiation on the characteristics of chitosan microparticles was investigated. The diclofenac sodium was incorporated into chitosan microparticles by spray-drying method. The c...

Background & Aim: Lemon verbena (Lippia citriodora H.B.K.) is a richly scented herb and has a long history as a sacred and medicinal plant. Select an appropriate medium in tissue culture is a necessity for success Experimental: To evaluate the effect of 10 medium of previous researches for Lippia micropropagation (1- MS medium supplemented with BAP (3 mgL-1) + IBA ...

2-Arachidonyl-glycerol (2-Ara-Gl) recently was identified as a putative endogenous ligand for cannabinoid receptor types CB1 and CB2 by competitive binding. More recent immune function assays demonstrated that 2-Ara-Gl possessed immunomodulatory activity. Because several plant-derived cannabinoids inhibit interleukin-2 (IL-2) expression, 2-Ara-Gl was investigated for its ability to modulate thi...

INTRODUCTION Although physiopathology of acute pancreatitis (AP) is not fully understood, the roles of reactive oxygen species (ROS) and changes of cytokines have been determined. AIM To investigate anti-inflammatory and anti-oxidant effects of glycyrrhizin (GL) on taurocholate-induced AP in rats. MATERIALS AND METHODS Thirty six rats were randomly divided into three groups as sham, AP and ...

With the increasing usage of indwelling medical devices in clinical practice, the frequency of fungal infections has increased, such as that of Candida albicans (C. albicans). Biofilms, a protected niche for microorganisms, are resistant to a range of current antifungal agents. Chitosan is a polyatomic biopolymer with advantageous biocompatibility, biodegradation, nontoxicity and antibacterial ...

BACKGROUND The main goal of endodontic treatment is to achieve cleaning and shaping prior to the filling process. OBJECTIVE This study aimed to evaluate, using atomic absorption spectrometry, the release of Calcium ions after the use of different chelating agents and protocols of agitation. METHOD Ninety human canine teeth were randomly assigned to one of nine groups (n=10), as follows: 1) ...

A main purpose of this paper is to explain how the theory of higher spin fields in flat D = 4 space and in AdS4 emerges as a result of the quantization of a superparticle propagating in so called tensorial superspaces which have the property of a ‘generalized conformal’ or simply General Linear (GL) flatness.

The pharmacokinetics of total and free prednisolone (PSL) in six healthy men, with or without pretreatment with oral glycyrrhizin (GL), was investigated to confirm whether oral administration of GL influences the metabolism of PSL in man. Each subject received an intravenous administration of 0.096 mg/kg of prednisolone hemisuccinate (PSL-HS) with or without pretreatment with 50 mg of oral GL f...