Chitosan, a natural biodegradable polymer is recommended for development of nanoparticles intended for chronic infection such as tuberculosis. Formulation and processing variables play a critical role in the formation of nanoparticles prepared with chitosan. The present study investigated the influence of polymer (chitosan) molecular weight, stabilizing agent (tween 80) concentration and stirri...

Three different Aspergillus Niger MTCC strains (872, 1785 and 2208) were used for the production of chitosan. Multivariate growth mediums in varying incubation periods were analyzed for the production. The produced chitosan was characterized by its physical appearance, moisture content (by means of gravimetric method), percentage of ash and solubility (through the Association of Official Agricu...

Chitosan is a naturally derived polymer with applications in a variety of industrial and biomedical fields. Recently, it has emerged as a promising material for biological functionalization of microelectromechanical systems (bioMEMS). Due to its unique chemical properties and film forming ability, chitosan serves as a matrix for the assembly of biomolecules, cells, nanoparticles, and other subs...

OBJECTIVE The purpose of the study was to design and evaluate novel functional chitosan hydrogels (chitosan-H-propolis, chitosan-H-propolis-nystatin and chitosan-H-nystatin) by using the chitosan-H polymer as "dual function restorative materials". MATERIALS AND METHODS The nystatin/antioxidant carrier gel was prepared by dispersion of the corresponding component in glycerol and 3% acetic acid...

BACKGROUND AND OBJECTIVES The most prevalent and worldwide oral disease is dental caries that affects a significant proportion of the world population. There are some classical approaches for control, prevention and treatment of this pathologic condition; however, the results are still not completely successful. Therefore new methods are needed for better management of this important challenge....

Crystalline chitosan was successfully prepared from crab tendons with aligned chitin molecules. Chitosan obtained preserved the tube structure with a suitable size for nerve conduits (t-chitosan tube). The chitosan tubes were compounded with hydroxy apatite (HAp) using an alternate soaking method (t-chitosan/HAp tube) to enhance the strength of the tube walls. HAp crystals formed in the walls o...

Recently, the attention of researchers has been drawn toward the synthesis of chitosan derivatives and their nanoparticles with enhanced antimicrobial activities. In this study, chitosan derivatives with different azides and alkyne groups were synthesized using click chemistry, and these were further transformed into nanoparticles by using the ionotropic gelation method. A series of chitosan de...

the chitosan nanoparticles used widely as a drug delivery systems recently. in the present study the echis carinataus snake venom loaded chitosan nanoparticles were prepared based on ionic gelation of tripolyphosphate and chitosan. the nanoparticles physicochemical characteristics, stability and biological activity of encapsulated venom were studied. the particles were spherical in shape and th...

Chitosan is a linear cationic biopolymer composed of glucosamine and N-acetyl-glucosamine that is only soluble in acidic aqueous solutions and precipitates when neutralized. However, it was recently discovered that chitosan dissolved in solutions containing glycerol phosphate was soluble at near neutral pH and produced a sol-gel transition when heated. Understanding this unique thermogelling sy...

The presence of contaminants in wastewater poses significant challenges to water treatment processes and environmental remediation. The use of coagulation-flocculation represents a facile and efficient way of removing charged particles from water. The formation of stable colloidal flocs is necessary for floc aggregation and, hence, their subsequent removal. Aggregation occurs when these flocs f...