A 54-year-old Chinese woman with a history of alcoholic cirrhosis and hypersplenism presented in 2003 with bilateral peri-orbital, malar, and glabellar swelling (Fig 1). She had a history of milder glabellar swelling 7 years ago. An incisional biopsy of the lesion taken at that time showed granulomatous inflammation. She subsequently failed to attend for follow-up. She came back when she discov...

A 70-year-old man with glaucoma was treated with eyedrops containing timolol maleate and brimonidine tartrate for >2 years. The patient presented with erythematous and oedematous pruritic lesions on both cheeks (Fig. 1a). Patch testing was performed with the Spanish Contact Dermatitis Research Group baseline series (TRUE Test®; Stallergenes Ibérica, Madrid, Spain; Brial Allergens GmbH,Greven, G...

An 18 month old girl with partial monosomy for the long arm of chromosome 22 is described. The karyotype was 46,XX,del(22)(pter----q13.1::q13.33----qter). To our knowledge this is the first report of monosomy for this specific segment of chromosome 22. Clinical features include developmental delay in all areas, hypotonia, macrosomia, full cheeks, eyebrows, and eyelids, mild epicanthus, wide nas...

Sir, Facial angiofibromas are flesh colored or red papules located centrofacially, especially on the nose, cheeks, and chin and represent a major criterion of tuberous sclerosis (TS). Unilateral facial angiofibromas (UFA) have been occasionally reported in literature. We present a case of UFA in a 36-year-old patient without other features of TS, review each case of previously described UFA and...

There are few reports of localized urticaria with symptoms to similar to livedo racemosa (reticularis) in adults. Here we describe a rare case of localized cold urticaria (grade 1) on the face of a 32-yearfemale. The results of an ice cube test showed a positive reaction on the affected area (her cheeks). Treatment with anti-histamine (second generation) tablets, warming and avoidance of cold e...

Use of barbed threads, available with uni- and bi-directional cogs or barbs, is a semi-invasive method of lifting sagging skin of the face. Areas treated with this method include the eyebrows, the cheeks, the jowls and the neck. Ease of use and a shorter down-time have made their use popular. Specific indications, operative procedures, risks and complications are described and some clinical res...

Cryptophthalmos is a rare congenital anomaly, characterized by extension of the skin continuously from forehead onto the cheeks and covering eyeballs. Although cryptophthalmos, as a part of Fraser syndrome, has been reported many times, isolated cryptophthalmos without systemic associations is very rare. We present a 6-month- old child with isolated bilateral complete cryptophthalmos, which to ...