Mutations in the centrosomal-ciliary gene CEP290/NPHP6 are associated with Joubert syndrome and are the most common cause of the childhood recessive blindness known as Leber congenital amaurosis (LCA). An in-frame deletion in Cep290 shows rapid degeneration in the rod-rich mouse retina. To explore the mechanisms of the human retinal disease, we studied CEP290-LCA in patients of different ages (...

Vitamin A deficiency is the most important cause of childhood blindness in lower and middle income countries, and contributes significantly to morbidity and mortality from common childhood infections. Beaton and colleagues’ metaanalysis of randomized community-based trials in eight countries concluded that vitamin A supplementation resulted in a 23% reduction in the mortality rates of children ...

a survey on the cause of blindness in iran was carried out among 870 blinds from all parts of the country. 305 people with the same cause, 27 with different causes were blind from both eyes and 538 were blind from one eye. in present paper the first ten causes of blindness is pointed out and these causes are compared in the three different zones of ten countries, also the cause of blindness in ...

PURPOSE To identify the causes of blindness and visual impairment among students in integrated schools for the blind in Nepal. METHODS A total of 778 students from all 67 integrated schools for the blind in Nepal were examined using the World Health Organization/Prevention of Blindness Eye Examination Record for Children with Blindness and Low Vision during the study period of 3 years. RESU...

BACKGROUND The present study is first of its kind to evaluate causes of visual impairment of blind students in Nepal and assess their need for low vision rehabilitation services. AIM To evaluate causes of vision impairment of students enrolled in blind schools in Nepal and assess the need for low vision rehabilitation services in these students. MATERIALS AND METHODS A survey was conducted ...

Childhood visual impairment is a major public health concern. The global financial burden of childhood-onset blindness greater than that adult-onset due to the longer span living. importance good vision for education and socialisation from an early age has prompted adoption screening in schools by many national eye care programmes Zimbabwe. Therefore, aim purpose this study were determine preva...

Da'wah activities in Islam are an obligation that must be carried out by every Muslim without exception. However, the perpetrators of da'wah also required to understand object da'wah, this statement has been applied mothers completing blindness Qur'an early childhood. Where success built mothers, is not because they good at processing words used their activities, but methods according needs mad...

Childhood cataracts are a major cause of treatable blindness. Early recognition, surgical intervention and appropriate follow-up after surgery can result in good visual outcomes. However, several factors may impact on the availability of such services, including lack of an available, affordable and accessible comprehensive eye care centre, financial limitations affecting coverage by the nationa...

Visual disability, particularly in children, can lead to a high mortality, economic loss and burden to the individual, family, community and the nation as a whole (Holden 2007; Roberts, Hiratsuka et al. 2010). Approximately 30,240 children are estimated to be blind in Nepal (Apex Body for Eye Health, Ministry of Health and Population, Nepal, 2011). One of the reasons of this high number might b...