OBJECTIVE The rupture of unstable carotid atherosclerotic plaques is one of the main causes of cerebrovascular ischemic events. There is need for circulating markers that can predict plaque instability and risk of stroke. Proinflammatory chemerin, leptin, and resistin, along with anti-inflammatory adiponectin, are adipokines with direct influence on vascular function. We investigated the associ...

Background The increase in the prevalence of obesity worldwide has led to non-alcoholic fatty liver disease (NAFLD) becoming one of the most common causes of chronic liver disease. Chemerin is a novel adipokine which regulates adipogenesis which is also a marker of systemic and vascular inflammation. Lipid accumulation product (LAP) is associated with the presenc...

INTRODUCTION Adipose tissue through the many secreted adipocytokines creates a highly active metabolic and endocrine organ. The evaluation of serum adipocytokine concentration in children with chronic kidney disease (CKD) could serve as a marker of cardio-vascular complication progression and an index of outcome in adulthood and after kidney transplantation. MATERIAL AND METHODS The aim of th...

Objective: To study the levels of serum adiponectin and chemerin in patients with nonalcoholic fatty liver disease(NAFLD) their diagnostic role.

BACKGROUND: Childhood obesity is a global threat with subsequent health problems among which and most important cardiovascular problems. It now claimed that adipokines secreted by adipose tissue are responsible for such consequences. Newly discovered chemerin apelin under investigation their link related co-morbidites. AIM: The aim of the present study was to assess serum levels in obese childr...

Chemerin peptides represent a recently identified component of the endogenous anti-inflammatory network that act via the G protein-coupled receptor ChemR23. The role of the chemerin peptide/ChemR23 pathway in phagocytosis, the clearance of apoptotic cells (efferocytosis), and the resolution of inflammation is unknown. In this article, we report that low picomolar concentrations of the chemerin ...

Breast cancer is the leading cause of cancer-related death among women in Saudi Arabia. Many studies have suggested a strong correlation between vitamin D and multiple types cancer. This study included 100 female patients with early or locally advanced breast Patients were recruited from King Faisal Hospital Taif City, Arabia, January 2020 to September 2020. We aimed association serum D, calciu...