نتایج جستجو برای: cfp10 fusion protein

تعداد نتایج: 1323442  

Anis Jafari, Mana Oloomi, Mehryar Habibi Roudkenari, Mohammad Ali Shokrgozar, Nader Shahrokhi, Saeid Bouzari,

Fusion of two genes at DNA level produces a single protein, known as a chimeric protein. Immunotoxins are chimeric proteins composed of specific cell targeting and cell killing moieties. Bacterial or plant toxins are commonly used as the killing moieties of the chimeric immunotoxins. In this investigation, the catalytic domain of Shiga-like toxin (A1) was fused to human granulocyte macrophage ...

Bovine ephemeral fever is an acute and arthropod-borne viral disease of cattle and water buffalo which occurs seasonally in most of the world tropical and subtropical regions. The epizootic feature of the disease has been reported in Iran with serious economic consequences. The surface glycoprotein G of bovine ephemeral fever virus (BEFV) is composed of 4 antigenic sites (G1-G4) and plays the m...

Mahrou Sadri Mohammad M Farajollahi Zohreh Sharifi,

Objective(s): Hepatitis C is a major cause of liver failure worldwide. Current therapies applied for this disease are not fully effective and produce side effects in most cases. Non-structural protein 3 helicase (NS3) of HCV is one of the key enzymes in viral replication and infection. Therefore, this region is a promising target to design new drugs and therapies against HCV infection. The aim ...

Journal: :iranian journal of basic medical sciences 0
mahrou sadri blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran department of medical biotechnology, faculty of allied medicine, iran university of medical sciences, tehran, iran mohammad m farajollahi department of medical biotechnology, faculty of allied medicine, iran university of medical sciences, tehran, iran zohreh sharifi blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran

objective(s): hepatitis c is a major cause of liver failure worldwide. current therapies applied for this disease are not fully effective and produce side effects in most cases. non-structural protein 3 helicase (ns3) of hcv is one of the key enzymes in viral replication and infection. therefore, this region is a promising target to design new drugs and therapies against hcv infection. the aim ...

Journal: :Journal of Histochemistry & Cytochemistry 2004

2017
Theresa M. Russell Louis S. Green Taylor Rice Nicole A. Kruh-Garcia Karen Dobos Mary A. De Groote Thomas Hraha David G. Sterling Nebojsa Janjic Urs A. Ochsner

Direct pathogen detection in blood to diagnose active tuberculosis (TB) has been difficult due to low levels of circulating antigens or due to the lack of specific, high-affinity binding reagents and reliable assays with adequate sensitivity. We sought to determine whether slow off-rate modified aptamer (SOMAmer) reagents with subnanomolar affinity for Mycobacterium tuberculosis proteins (antig...

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