background: clinical information about stroke in the vertebrobasilar territory has lagged behind that for anterior circulation syndrome. this is the first report from posterior circulation syndrome registry in iran.   methods: consecutive patients with brain infarction in vertebrobasilar territory admitted to ghaem hospital, mashhad were enrolled in a prospective study during 2006-2007. diagnos...

Background: Hyperthyroidism as a risk factor for stroke is not conclusive. There are no definite data on the relationship between ischemic cerebrovascular injury and hyperthyroidism. This study was designed to define whether the outcomes of post-ischemic stroke injury are influenced by chronic hyperthyroidism. Methods: Two groups of hyperthyroid (HT) and control euthyroid rats of equal numbers ...

In acute ischemic stroke patients with major intracranial vessel occlusion due to infective endocarditis, treatment modalities are not well established. A 40-year-old woman presented with acute stroke due to left middle cerebral artery occlusion. She was successfully treated with intra-arterial mechanical thrombectomy, and the subsequent clinical outcome was favorable. Pathological analysis of ...

In 48 patients dying within 15 days following a supra-tentorial cerebral infarct, the presence of hemorrhagic infarction at autopsy was related to a cardiac embolic cause of the infarct, and to the cause of death. Hemorrhagic infarcts were more common among patients dying from brain herniation than among those dying from a non-cerebral cause. Cardiac embolic strokes were more often hemorrhagic ...

Letters to the Editor will be published, if suitable, as space permits. They should not exceed 1,000 words (typed double-spaced) in length and may be subject to editing or abridgment. To the Editor: The relationship between embolism and thrombosis as a cause of ischemic stroke is far from established. Not all ischemic strokes in patients with a cardiac source are caused by cardio-genic embolism...

BACKGROUND Microvascular dysfunction posttreatment of stroke with recombinant human tissue-type plasminogen activator (rht-PA) constrains the therapeutic window to 3 hours. Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) promote vascular thrombolysis and reduce the inflammation response. We therefore investigated the neuroprotective effects of a combination of atorvastatin ...

BACKGROUND AND PURPOSE The aim of the present study was to investigate the impact of different stroke subtypes on the glymphatic system using MRI. METHODS We first improved and characterized an in vivo protocol to measure the perfusion of the glymphatic system using MRI after minimally invasive injection of a gadolinium chelate within the cisterna magna. Then, the integrity of the glymphatic ...

True three-dimensional proton nuclear magnetic resonance (NMR) imaging was performed on an 84-year-old man following a recent cerebral embolic infarction. NMR data obtained using different pulse sequences were inter-correlated, stressing the significance of image appearance in terms of the NMR tissue parameters. Planes selected for display from the three-dimensional data set allowed optimal vis...

Background & Aims: Sleep disorders are common complains in patients with cerebral stroke; studies on these issues are limited. We aimed to evaluate the sleep changes in patients with supratentorial ischemic stroke. Methods: In this cross sectional study, 38 patients (19 patients in supratentorial ischemic stroke group and 19 people in control group) were evaluated. Total sleep time, sleep effic...

INTRODUCTION  In the literature, the incidence of oropharyngeal dysphagia in patients with cerebrovascular accident (AVE) ranges 20-90%. Some studies correlate the location of a stroke with dysphagia, while others do not. OBJECTIVE  To correlate brain injury with dysphagia in patients with stroke in relation to the type and location of stroke. METHOD  A prospective study conducted at the Ho...