Teubner BJ, Keen-Rhinehart E, Bartness TJ. Third ventricular coinjection of subthreshold doses of NPY and AgRP stimulate food hoarding and intake and neural activation. Am J Physiol Regul Integr Comp Physiol 302: R37–R48, 2012. First published October 19, 2011; doi:10.1152/ajpregu.00475.2011.—We previously demonstrated that 3rd ventricular (3V) neuropeptide Y (NPY) or agouti-related protein (Ag...

Evidence in rats suggests that central oxytocin (OT) signaling pathways contribute to suppression of food intake during dehydration (i.e., dehydration anorexia). The present study examined water deprivation-induced dehydration anorexia in wild-type and OT -/- mice. Mice were deprived of food alone (fasted, euhydrated) or were deprived of both food and water (fasted, dehydrated) for 18 h overnig...

Over the past decade, there has been a tremendous increase in the understanding of the molecular and neural mechanisms that control food intake and body weight. Yet eating disorders and cachexia are still common, and obesity cases are rising at alarming rates. Thus, despite recent progress, an increased understanding of the molecular and neural substrates that control body weight homeostasis is...

Experiments in animals suggest that the neuropeptide oxytocin acts as an anorexigenic signal in the central nervous control of food intake. In humans, however, research has almost exclusively focused on the involvement of oxytocin in the regulation of social behavior. We investigated the effect of intranasal oxytocin on ingestion and metabolic function in healthy men. Food intake in the fasted ...

BACKGROUND The recent dietary reference intakes publication provides updated information on the physiologic and dietary requirements for zinc and proposes new tolerable upper intake levels. OBJECTIVE We analyzed dietary intake data of US preschool children to determine the prevalence of inadequate and excessive intakes of zinc. DESIGN Diets of 7474 nonbreastfeeding preschool children in the...

introduction: there is no comprehensive study on the effect of folate on food intake therefore the present study was carried out to determine the effect of folate supplementation on serum concentrations of leptin and grehlin and food intake in male wistar rats. methods: the study was carried out for 42 days during which the animals were weighed weekly their food and water intakes were measured ...

The receptor subtypes that mediate the effects of neuropeptide Y (NPY) on food intake have not been clearly defined. The NPY Y4 receptor has been identified recently as a potential mediator of the regulation of food intake. The purpose of the present study was to characterize the central site of action of the Y4 receptor using a combination of neuroanatomical and physiological approaches. Using...