BACKGROUND In survival analyses of longitudinal data, death is often a competing event for the disease of interest, and the time-to-disease onset is interval-censored when the diagnosis is made at intermittent follow-up visits. As a result, the disease status at death is unknown for subjects disease-free at the last visit before death. Standard survival analysis consists in right-censoring the ...

The use of Kalman filtering, as well as its nonlinear extensions, for the estimation of system variables and parameters has played a pivotal role in many fields of scientific inquiry where observations of the system are restricted to a subset of variables. However in the case of censored observations, where measurements of the system beyond a certain detection point are impossible, the estimati...

The censored linear regression model, also referred to as the accelerated failure time (AFT) model when the logarithm of the survival time is used as the response variable, is widely seen as an alternative to the popular Cox model when the assumption of proportional hazards is questionable. Buckley and James [Linear regression with censored data, Biometrika 66 (1979) 429-436] extended the least...

Parameters of quantitative genetic models have traditionally been estimated by either algebraic manipulation of familial correlations (or familial mean squares), biometric model fitting, or multiple-group covariance structure analysis. With few exceptions, researchers who have used these methods for the analysis of twin data have assumed that their data were multinormal and, consequently, have ...

There is a growing interest in the analysis of survival data with a cured proportion particularly in tumor recurrences studies. Biologically, it is reasonable to assume that the recurrence time is mainly affected by the overall health condition of the patient that depends on some covariates such as age, sex, or treatment type received. We propose a semiparametric frailty-Cox cure model to quant...

Powell's (1984, Journal of Econometrics 25, 303}325) censored least absolute deviations (CLAD) estimator for the censored linear regression model has been regarded as a desirable alternative to maximum likelihood estimation methods due to its robustness to conditional heteroskedasticity and distributional misspeci"cation of the error term. However, the CLAD estimation procedure has failed in ce...

Two common statistical problems in pooling survival data from several studies are addressed. The first problem is that the data are doubly censored in that the origin is interval censored and the endpoint event may be right censored. Two approaches to incorporate the uncertainty of interval-censored origins are developed, and then compared with more usual analyses using imputation of a single f...

Thus far, likelihood-based interval estimates for quantiles have not been studied in the literature on interval censored case 2 data and partly interval censored data, and, in this context, the use of smoothing has not been considered for any type of censored data. This article constructs smoothed weighted empirical likelihood ratio confidence intervals (WELRCI) for quantiles in a unified frame...

In this paper, based on a left censored data from the twoparameter Pareto distribution, maximum likelihood and Bayes estimators for the two unknown parameters are obtained. The problem of reconstruction of the past failure times, either point or interval, in the left-censored set-up, is also considered from Bayesian and non-Bayesian approaches. Two numerical examples and a Monte Carlo simulatio...