نتایج جستجو برای: cembrane diterpene

تعداد نتایج: 1398  

2011
Jui-Hsin Su Zhi-Hong Wen

Chemical examination of the Taiwanese soft coral Sinularia triangular led to the isolation of five cembrane-based diterpenoids 1-5, including two new metabolites, triangulenes A (1) and B (2). The structures of the new metabolites were determined on the basis of extensive spectroscopic analysis, particularly mass spectroscopy and 2D NMR ((1)H-(1)H COSY, HMQC, HMBC, and NOESY) spectroscopy. Meta...

Journal: :Angewandte Chemie International Edition 2020

Journal: :Natural Product Communications 2007

Journal: :Chemical and Pharmaceutical Bulletin 2011

2017
Xinli Pan Nicole Domin Sebastian Schieferdecker Hirokazu Kage Martin Roth Markus Nett

The genome of the predatory bacterium Herpetosiphon aurantiacus 114-95T harbors a number of biosynthesis genes, including four terpene cyclase genes. To identify the terpenes biosynthesized from H. aurantiacus 114-95T, we fed the strain with 13C-labeled glucose and, subsequently, searched for characteristic mass shifts in its metabolome. This approach led to the discovery of a new natural produ...

Journal: :Methods in enzymology 2012
Michael J Smanski Ryan M Peterson Ben Shen

Diterpenoid natural products cover a vast chemical diversity and include many medicinally and industrially relevant compounds. All diterpenoids derive from a common substrate, (E,E,E)-geranylgeranyl diphosphate, which is cyclized into one of many scaffolds by a diterpene synthase (DTS). While diterpene biosynthesis has been extensively studied in plants and fungi, bacteria are now recognized fo...

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