Adenoids and tonsils are active lymphoid organs and play an important role against invading antigens of upper aerodigestive tract in children. The present study analyzes the changes in cellular and humoral immunity of children six months after adenotonsillectomy. The study population consisted of 30 children whit chronic adenotonsillar hypertrophy and 30 age-matched healthy children. In all chi...

Sustained inflammation of the vessel walls occurs in a large number of systemic diseases (ranging from atherosclerosis to systemic vasculitides, thrombotic microangiopathies and connective tissue diseases), which are ultimately characterized by ischemia and end-organ failure. Cellular and humoral innate immunity contribute to a common pathogenic background and comprise several potential targets...

using complement fixation technique, serial serum samples from 15 patients undergoing surgical removal of malignant tumors were assayed for the presence of tumors antibodies against the cellular fractions of both normal and carcinomatous tissue. antibody responses against tumor associated antigens were detected in four cases. in all cases antibody activity was directed only against the supernat...

hepatitis b virus (hbv) is the most prevalent viral infection and is among the leading causes of human liver diseases. nearly 360 millions of people are world widely infected with prolonged forms of hepatitis b including active and inactive chronic forms. chronic hepatitis b (chb) is associated with cirrhosis and hepatocellular carcinoma (hcc) in patients suffering from congenital and/or acquir...

cd40 is recognized as a member of tumor necrosis factor receptor super family. it is expressed by the immune and non-immune cells. its interaction with cd40 ligand (cd154) brings about  a regulatory effect on  the cellular and humoral immunity. the pathway of cd40-cd154 is influential in various diseases. investigations on such diseases have revealed dimensional mechanisms whereby this route in...

The literature concerned with the types of cells that participate in the humoral and cell-mediated immune response has been reviewed. It is postulated that the initial cells that are involved in mediating both types of immunity are functionally identical in that both are antigen-reactive cells. In the case of the humoral immune response, the interaction of the antigen-reactive cells with the an...