There is an infinite number of interactions between morphogenetic processes of different time and space scales. How do these unfold in a regular series of mass morphogenetic movements to produce a basically simple and reproducible structure? I present a new morphogenetic concept -- the spatial unfolding (SU) of cell movements, whose definition rests on the correspondence between the continuous ...

I took great interest in the recent article regarding the retinal pigment epithelium (RPE) transplantation by Falkner-Radler et al. I agree that RPE cell transplantation might be a novel therapeutic option for patients in the antivascular endothelial growth factor (anti-VEGF) era, where antiVEGF fails to improve visual acuity. This is the case in RPE tear, massive subretinal haemorrhage or anti...

PURPOSE To compare the clinical results of cultivated oral mucosal epithelial cell sheet transplantation (COMET) of substrate-free sheets with those of COMET of amniotic membrane (AM)-based sheets. METHODS Sixteen eyes receiving COMET of substrate-free sheets (substrate-free group) were studied retrospectively and compared with disease-, age-, and ocular surface status-matched eyes undergoing...