نتایج جستجو برای: celiac gluten senssitivity
تعداد نتایج: 14748 فیلتر نتایج به سال:
Celiac disease is a multisystem resistant based issue that is activated by the ingestion of gluten in hereditarily defenseless people. The predominance of celiac disease has ascended in late decades and is at present around 1% in most Western populaces. The explanation behind this ascent is obscure, albeit natural elements identified with the cleanliness speculation are suspected. The pathophys...
BACKGROUND & AIMS Early nutrition may affect the risk of celiac disease. We investigated whether amount of gluten in diet until 2 years of age increases risk for celiac disease. METHODS We performed a 1-to-3 nested case-control study of 146 cases, resulting in 436 case-control pairs matched for sex, birth year, and HLA genotype generated from Swedish children at genetic risk for celiac diseas...
Incorporation of L-leucine-(14)C into proteins and immunoglobulins in vitro was determined in jejunal biopsy specimens from normal volunteers, patients with celiac sprue before and after introduction of gluten into the diet, patients with Whipple's disease in remission, and patients with immune deficiency states. Values for incorporation of L-leucine-(14)C into total and soluble protein by biop...
Autoantibodies specific for the enzyme transglutaminase 2 (TG2) are a hallmark of the gluten-sensitive enteropathy celiac disease. Production of the Abs is strictly dependent on exposure to dietary gluten proteins, thus raising the question how a foreign Ag (gluten) can induce an autoimmune response. It has been suggested that TG2-reactive B cells are activated by gluten-reactive T cells follow...
Theterm gluten intolerance may refer to three types of human disorders: autoimmune celiac disease (CD), allergy to wheat and non-celiac gluten sensitivity (NCGS). Gluten is a mixture of prolamin proteins present mostly in wheat, but also in barley, rye and oat. Gluten can be subdivided into three major groups: S-rich, S-poor and high molecular weight proteins. Prolamins within the groups posses...
The celiac disease is an autoimmune gastrointestinal disorder caused by gluten from wheat, rye or barley. In genetically predisposed persons, gluten induces the immune-mediated inflammation of small intestinal mucosa. Histological lesions include intraepithelial lymphocytosis, crypt hypertrophy and villous atrophy, resulting in malabsorption of micro- and macronutrients. The only treatment for ...
Celiac disease is chronic disease with immune disorder which is connected with the allergy reaction on molecule of gluten and prolamine. Celiac disease is expressed in persons with genetic susceptibility. The aim of the study was to follow adherence to gluten-free diet. We designed cross-sectional study where was recruited 125 volunteers, children at age 9 15 years old, with diagnosis of celiac...
Celiac disease is an intestinal autoimmune disorder, triggered by ingestion of a gluten-containing diet in genetically susceptible individuals. The genetic predisposition is related to human leukocyte antigen (HLA) class II genes, especially HLA-DQ2-positive patients. The prevalence of celiac disease has been estimated to be ~1% in Europe and the USA, but it is rarer and/or underdiagnosed in As...
Celiac disease is one of the most common autoimmune diseases with a prevalence rate of 0.5-1% in the total population. Diagnosis has increased in recent years; however, many cases of the disease still seem to be diagnosed late. Although the rheumatic manifestations of celiac disease are not uncommon, they are often overlooked. A 30-year-old female patient referred to the rheumatology clinic of ...
BACKGROUND The relationship between the risk of celiac disease and both the age at which gluten is introduced to a child's diet and a child's early dietary pattern is unclear. METHODS We randomly assigned 832 newborns who had a first-degree relative with celiac disease to the introduction of dietary gluten at 6 months (group A) or 12 months (group B). The HLA genotype was determined at 15 mon...
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