Cell culture data indicate that quercetin and catechin may affect the activity of phase II and antioxidant enzymes. However, little is known about the impact of dietary flavonoids in vivo. Therefore, the present study aimed to investigate the in vivo effects of the flavonoids quercetin and catechin on mRNA and activity levels of phase II enzymes glutathione-S transferase (GST) and NAD(P)H quino...

The absorption and splanchnic metabolism of different flavonoids (namely quercetin, kaempferol, luteolin, eriodictyol, genistein, and catechin) were investigated in rats after an in situ perfusion of jejunum plus ileum (14 nmol/min). Net transfer across the brush border ranged widely according to the perfused compound (from 78% for kaempferol to 35% for catechin). This variation seems linked to...

The flavanoid catechin and heterogenous samples of oligomeric proanthocyanidins extracted from various sources were compared for their ability to inhibit the biochemical and biological effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in mouse epidermis in vivo. Topical applications of catechin fail to alter the hydroperoxide response to TPA but inhibit the induction of ornithine decarboxyl...

Guava (Psidium guajava L.), is adapted to an extensive range of soils, however, its development is strongly affected by salinity. Environmental stresses are of the major and influential factors in the amount of secondary metabolites, especially phenolic compounds present in plants. The purpose of this investigation was to study the leaf antioxidant and flavonoid contents (catechin, quercetin an...

Catechin has been reported to possess many advantageous for practical application due its distinctive antioxidant and anti-inflammatory performance. This paper reports the in-silico characterization of single stranded-DNA (ssDNA) aptamers, specific catechin. 28 primary sequences from DNA-aptamers library screened via systemic evolution ligands by exponential enrichment (SELEX) previous research ...

in this study, the amount of total phenol, chlorogenic acid, catechin, quercetin, phloridzin, cyanidin and antioxidant activity of apple (malus domestica) skin and flesh of six iranian cultivars, including: ‘golab kohanz’, ‘sib torsh dirras’, ‘ghara yapragh’, ‘torkman’, ‘ghezel alma’ and ‘abbasi mashhad’, and four commercial cultivars including: ‘golden delicious’, ‘red delicious’, ‘braeburn’ a...

The high-yielding synthesis of enantiomerically pure epicatechin gallate analogues where the A and/or B-ring hydroxylation is reduced or altered has been achieved by optimising routes to the catechin stereochemistry. The B-ring analogues were synthesised by using an electrophilic ring closure onto an enantiomerically enriched epoxide as a key step. The A and B-ring hydroxyl-deleted analogues we...

Let H be a quasi-Hopf algebra. We show that any H-bimodule coalgebra C for which there exists an H-bimodule coalgebra morphism ν : C → H is isomorphic to what we will call a smash product coalgebra. To this end, we use an explicit monoidal equivalence between the category of two-sided two-cosided Hopf modules over H and the category of left Yetter-Drinfeld modules over H. This categorical metho...