Optically active highly functionalized 3,4-dihydropyridin-2-ones were synthesized by N-heterocyclic carbene-catalyzed [4+2] enantioselective cycloaddition of ketenes and 1-azadienes.

A nickel-catalyzed [2+2+2] cycloaddition of two molecules of aryne and an alkene moiety in a alpha,omega-diene afforded 9,10-dihydrophenanthrene derivatives in good yields.

Elastin-like polypeptides (ELPs) functionalized with azide or alkyne groups were produced biosynthetically and coupled via the Cu-catalyzed azide-alkyne cycloaddition to a variety of (bio)molecules.

Phosphine-catalyzed [3 + 2] cycloaddition of Morita-Baylis-Hillman carbonates with sulfamate-derived cyclic imines has been developed, affording sulfamate-fused dihydropyrroles in moderate to good yields.

A simple flavin-based catalytic system is able to transform light into chemical output with amplified response utilizing a Cu(I)-catalyzed cycloaddition reaction.

In the present work, impact of Lewis acid (LA) catalysts BF3, BCl3, and BBr3 on the kinetics andregioselectivity of 1,3-dipolar cycloaddition (1,3-DC) reaction between azidobenzene and acroleinwas theoretically studied using B3LYP/6-31G* level. Our results indicate while the uncatalyzed 1,3-DC reaction under investigation takes place via a non-polar, non-regioselective, and lowasynchronous proc...

A highly stereoselective desymmetrization reaction of δ,δ-diaryl-α-diazo-β-ketoesters catalyzed by chiral dirhodium carboxylates forms aromatic cycloaddition products in up to 97% ee.

1,2,3-Triazoles are an important class of heterocycles, which display very large spectrum of biological activities and are widely used as pharmaceuticals and agrochemicals. Compounds containing 1,2,3-triazoles have also found industrial applications as corrosion inhibitors, lubricants, dyes, and photostabilizers. As such, the development of new and more general methods for their preparation is ...