The role of antioxidants in maintaining the functional integrity of adrenocortical cells during in vitro exposure to endosulfan, an organochlorine pesticide, was investigated in rainbow trout (Oncorhynchus mykiss). Aminotriazole (ATA), an inhibitor of catalase (CAT), L-buthionine sulfoximine (L-BSO), an inhibitor of glutathione (GSH) synthesis, and N-acetyl cysteine (NAC), a glutathione precurs...

The aim of this paper was to study the activity of liver superoxide dismutase and catalase and the concentration of liver malondialdehyde in rats intoxicated with chlorfenvinphos, an organophosphate widely used as an insecticide. The study was carried out on male Wistar rats weighing 180-230 g. The rats were divided into two groups: examined receiving oil solution of chlorfenvinphos in doses of...

In the present study, kidney tissues were selected to measure the catalase (CAT) enzyme activity due to their responsibility in the elimination of the compounds generating reactive oxygen species (ROS). Variation in Oreochromis niloticus kidney CAT activity (114.33±0.33 to 159.5±0.03) was observed throughout the study period. During first week of experimental trial, higher CAT activity (159.5±0...

PURPOSE To test in mice with experimental autoimmune encephalomyelitis (EAE) a strategy designed to treat patients at risk for axonal degeneration and persistent visual loss from optic neuritis and multiple sclerosis. METHODS The authors cloned the human extracellular superoxide dismutase (ECSOD) or catalase (CAT) gene into recombinant adenoassociated virus (AAV). Transgene expression was eva...

Rationale:Androgenetic alopecia is not considered a life threatening disease but can have serious impacts on the patient's psychosocial life. Genetic, hormonal, and environmental factors are considered responsible for the presence of androgenetic alopecia. Recent literature reports have proved the presence of inflammation and also of oxidative stress at the level of dermal papilla cells of pati...

Laboratory studies were conducted to determine the effects of different concentrations of Cu, Cd, Zn and mixture (equal concentrations from the three heavy metals) on growth and some oxidative stress (catalase and glutathione reductase) on Scenedesmus obliquus (microalgae) after exposure for 24, 48, and 96 h. In addition, the uptake of Cu, Cd and Zn were determined in the culture medium after 2...

In this study, it was aimed to investigate the effects of salinity, which is an important environmental problem, in cultivation ornamental plants (such as zinnia) and irrigation with high salt water, especially on antioxidant defense mechanism. For purpose, two Zinnia species were irrigated by different concentrations saline water (50, 100, 150, 200 mM NaCl); salinity superoxide dismutase (SOD)...

ABSTRACT Low-temperature storage is one of the most effective techniques to maintain quality and durability cut flowers. Both maintenance are dependent on plant metabolism factors such as antioxidant system. The objective was evaluate effect low-temperature precooling after harvest, calla lily [Zantedeschia aethiopica (L.) K. Spreng] concerning system, levels hydrogen peroxide (H2O2), malondial...

Seasonal changes in the total phenolic content, flavonoid content, specific activity of the enzyme polyphenol oxidase (PPO) and that of the antioxidative enzymes-catalase (CAT) and peroxidases (POX) were analyzed in three leafy liverworts, namely Solenostoma crenulata, Chiloscyphus gollani and Fossombronia himalayensis. In the rainy season (July–September), the plants were in their young juveni...

OBJECTIVE Myeloid lineage cells (MLCs) such as macrophages are known to play a key role in postischemic neovascularization. However, the role of MLC-derived reactive oxygen species in this process and their specific chemical identity remain unknown. METHODS AND RESULTS Transgenic mice with MLC-specific overexpression of catalase (Tg(Cat-MLC) mice) were created on a C57BL/6 background. Macroph...