BACKGROUND Radial movement of the arterial wall is a well-known indicator of the mechanical properties of arteries in arterial disease examinations. In the present study, two different motion estimation methods, based on the block-matching and maximum-gradient algorithms, were examined to extract the radial displacement of the carotid artery wall. METHODS Each program was separately implement...

The stationary flow of blood in a two-dimensional model of the bifurcation of the human carotid artery is simulated numerically using a finite element method. The Reynolds number is taken as equal to 300, corresponding to the value during the end-diastolic phase of the heart cycle. As constitutive equations, the Newtonian model and the non-Newtonian power-law and Casson models are used. The cho...

We have previously shown that the decrease in large artery distensibility observed in patients with essential hypertension (HT group) was primarily due to an increase in distending pressure and not to hypertension-associated structural modifications of the artery, suggesting a functional adaptation of the wall material. To evaluate the elastic properties of the wall material of the common carot...

INTRODUCTION. We first present an experimental determination of carotid artery properties by using strips of human carotid artery. The strips were taken in the longitudinal and in the circumferential directions assuming that the carotid artery wall has the orthotropic characteristics. The material was subjected to uniaxial tension and the stress-stretch curves were obtained for various rates of...

BACKGROUND Matrix metalloproteinase (MMP) activation plays a key role in vascular remodeling. RP782 is a novel indium (111)In-labeled tracer with specificity for activated MMPs. We hypothesized that RP782 can detect injury-induced vascular remodeling in vivo. METHODS AND RESULTS Left common carotid artery injury was induced with a guidewire in apolipoprotein E(-/-) mice. Sham surgery was perf...

Purpose. Atherosclerosis is a diseased condition of blood vessel. It causes partial blockage in lumen of vessel and affects hemodynamic of localized flowing blood. Complex geometries like region of bifurcation also affects hemodynamic to a larger extent. Complexity further increases in presence of stenoses at region of bifurcation. Such morphological change in vessel largely affects parent as w...

BACKGROUND Coronary artery bypass grafting ranks as one of the most frequent operations worldwide. The presence of carotid artery stenosis may increase the stroke rate in the perioperative period. Routine preoperative noninvasive assessment of the carotid arteries are recommended in many institutions to reduce the stroke rate. METHODS 271 consecutive patients undergoing coronary artery bypass...

conclusions the relationship between cac found on dental panoramic radiographs and two cva risk factors--hypertension and mi-- was significant. therefore, it seems that detection of cac on panoramic images of dental patients must be considered by dentists. results among 200 studied samples, 22 of the patients (11%) had carotid artery calcification on the dental panoramic radiograph. in total, 5...

BACKGROUND AND PURPOSE Carotid plaque rupture depends on the various types of mechanical stresses. Our objective was to determine the multiaxial mechanical characteristics of atherosclerotic plaque and adjacent segment of the common carotid artery. METHODS A novel noninvasive echotracking system was used to measure intima-media thickness, diameter, pulsatile strain, and distensibility at 128 ...

Introduction: Nitroglycerin is a fast-acting drug that rapidly dilates coronary arteries and thus increases blood flow to these vessels, and increases the blood flow through the lateral vessels to low blood areas. It also reduces both end diastolic pressure and volume of the left ventricular. However, the effect of nitroglycerin on the circulation hemodynamic is not known. Caro...