One has only to compare the 1980 American College of Cardiology (ACC) Annual Scientific Session program to the 1997 program in Anaheim to be amazed at the marked increase in the number of scientific abstracts presented (400 compared with 2,138). Why, then, is there widespread concern about the future of cardiovascular research in the United States? (1–4). Before addressing this question, it is ...

“W hat will be the next best thing in cardiovascular research?” This was the loaded question recently posed in a panel discussion at the American Heart Association Council on Basic Cardiovascular Sciences (BCVS) 2017 Scientific Sessions, held in Portland, OR, from July 10 to 13. The panelists made clear the challenge to predict the next major breakthrough, with most scientists in the room hopin...

American Heart Association. All rights reserved. Print ISSN: 1942-325X. Online ISSN: 2011 Copyright © Avenue, Dallas, TX 72514 Circulation: Cardiovascular Genetics is published by the American Heart Association. 7272 Greenville DOI: 10.1161/CIRCGENETICS.111.961003 2011;4;463-464; Circ Cardiovasc Genet Manuel Mayr Recent Highlights of Metabolomics in Cardiovascular Research http://circgenetics.a...

Proteomic technologies are used to study the complexity of proteins, their roles, and biological functions. It is based on the premise that the diversity of proteins, comprising their isoforms, and posttranslational modifications (PTMs) underlies biology. Based on an annotated human cardiac protein database, 62% have at least one PTM (phosphorylation currently dominating), whereas 25% have more...

Is it better to have a heart attack in the United States or Canada? Ecological studies are epidemiological evaluations in which the unit of analysis is populations, or groups of people, rather than individuals.1 They can answer important questions such as the question posed above that cannot easily be answered using any other form of study design. Ecological studies are conducted by researchers...