The Relationship of Intracellular Depolarization Rates and Contractility in the Dog Ventricle in Situ: Effects of Positive and Negative Inotropic Agents. JACK K. PRUETT AND EUGENE F. WooDs 1 Calcium Movements in Resting and Stimulated Isolated Rabbit Atria. DAVID G. TEIGER AND ALFRED FARAH 8 Studies on the Cardiovascular Effects of Synthetic Vasopressin. JIR0 NAKANO 19 A New Anorexic Agent, Wy-...

The Relationship of Intracellular Depolarization Rates and Contractility in the Dog Ventricle in Situ: Effects of Positive and Negative Inotropic Agents. JACK K. PRUETT AND EUGENE F. WooDs 1 Calcium Movements in Resting and Stimulated Isolated Rabbit Atria. DAVID G. TEIGER AND ALFRED FARAH 8 Studies on the Cardiovascular Effects of Synthetic Vasopressin. JIR0 NAKANO 19 A New Anorexic Agent, Wy-...

Cardiovascular Magnetic Resonance (CMR) has become a primary tool for non-invasive assessment of cardiovascular anatomy, pathology and function. Existing contrast agents have been utilised for the identification of infarction, fibrosis, perfusion deficits and for angiography. Novel ultrasmall superparamagnetic particles of iron oxide (USPIO) contrast agents that are taken up by inflammatory cel...

Patients after a myocardial infarction are at increased risk of adverse cardiovascular outcomes. They require aggressive secondary preventive measures to control cardiovascular risk factors, and prescription of some pharmacological agents. Compelling data derived from randomized controlled trials have shown the benefits of aspirin (or clopidogrel), statins, beta-blockers and angiotensin-convert...

A. Estrogens and primary prevention of cardiovas-cular disease B. Comparison of statins with estrogens for primary prevention of cardiovascular disease C. Effects of statins on new coronary events and survival D. Other agents with potential for prevention of car-diovascular disease E. Secondary prevention of cardiovascular disease III. Prevention and Treatment of Osteoporosis A. Estrogen therap...

INTRODUCTION Falls rank among the most serious medical problems in elderly persons, having psychological as well as social consequences. With several hundred fall risk factors known at present, it is necessary to select those that occur most frequently in a particular population. Only then will it be possible to implement effective fall prevention programmes with the aim of increasing awareness...

Philippe Gabriel Steg, MD Ronan Roussel, MD, PhD Glucose control is a key aspect of diabetes management. After concerns about the cardiovascular safety of several classes of antihyperglycemic agents, culminating with concerns about thiazolidinediones, the US Food and Drug Administration implemented a guidance statement in 2008 (strongly) recommending the demonstration of cardiovascular safety o...

A combination of metabolic disorders manifested by increased blood glucose levels causes Diabetes mellitus. Patients with diabetes are more prone to morbidity and rate mortality compared the general population, a substantial contribution healthcare costs. One significant risk factors for cardiovascular problems is Mellitus. Hence, additional beneficial effect has been reported in various new an...

PURPOSE To compare the medication history error rate of the emergency department (ED) pharmacy technician with that of nursing staff and to describe the workflow environment. METHODS Fifty medication histories performed by an ED nurse followed by the pharmacy technician were evaluated for discrepancies (RN-PT group). A separate 50 medication histories performed by the pharmacy technician and ...

Calcium antagonists comprise 2 main subclasses, dihydropyridines and nondihydropyridines, and have been studied extensively in hypertensive patients. Early meta-analyses suggested that short-acting calcium antagonists were associated with higher mortality rates resulting from cardiovascular events and other etiologies. Recent meta-analyses failed to show any substantive difference between long ...