Appendiceal carcinoids are the most frequent tumors arising from appendix, comprising between 32 and 57% of all appendiceal tumors. The gross appearance appendix showed perforation at tip with 30 ml peri-appendicular collection. On histopathological examination, carcinoid tumor on was found cells arranged in tubules, acini nests infiltrating muscularis propria sub serosa. Perineural vascular in...

Carcinoid tumors are rare, indolent neuroendocrine tumors that are often associated with a syndrome characterized by episodic flushing, secretory diarrhea, bronchospasm, and hypotension-the carcinoid syndrome. Cardiac involvement occurs in one-half to two-thirds of patients with carcinoid syndrome and is associated with a worse clinical outcome. Carcinoid heart disease is characterized by endoc...

BACKGROUND The term carcinoid (Karzinoide) was coined by German pathologist Oberndorfer in 1907. Primary testicular carcinoid tumors (TCT) are rare, constituting 0.23% of all testicular tumors. In this report we describe a case of primary TCT of the testis and present the results of an extensive literature review to cover all the aspects of carcinoid tumor, including the definition, classificat...

Lymphomatous involvement of the appendix is rare and most of them are found accidentally from appendectomies to treat appendicitis. Here we report three cases of primary lymphoma of appendix of 10 year-old boy, 23-year-old man and 24-year-old woman that presented with abdominal pain to our hospital and the tumors were discovered during routine appendectomy for suspected "appendicitis". Our case...

Carcinoid Heart Disease (CHD) is one of the rare causes of acquired valvular heart disease. CHD develops as a systemic manifestation of metastatic neuroendocrine tumors (NETs). When these tumors metastasize to the liver, they can release vasoactive amines into the systemic circulation, which can result in carcinoid syndrome and CHD. The key for diagnosing CHD is a thorough history and physical ...

PATIENT Female, 67. FINAL DIAGNOSIS Pulmonary carcinoid tumor. SYMPTOMS Abnormal shadow on chest X-ray. MEDICATION -. CLINICAL PROCEDURE -. SPECIALTY Pulmonology. OBJECTIVE Rare disease. BACKGROUND Although pulmonary carcinoid tumors are generally considered to represent a low-grade malignancy, atypical carcinoids are more aggressive than typical carcinoids, metastasizing more com...

exome sequencing studies of sporadic tumors, this discovery is noteworthy in that it provides a new and rational target for investigation. IPMK is an inositol phosphate kinase, and the authors describe a link between IPMK and p53-mediated apoptosis. It will be important to understand the importance of this interaction in the context of homeostasis and transformation of enteroendocrine cells. Pr...

Carcinoid tumors are relatively rare neuroendocrine malignancies most commonly originating from enterochromaffin cells in the gastrointestinal tract. The incidence is 1 in 100 000 of the general population.1 They usually grow slowly over years, commonly causing no symptoms at all until they become large or have metastasized. Carcinoid tumors of midgut origin may secrete large amounts of vasoact...

OBJECTIVE carcinoid tumors (CTs) represent the commonest neuroendocrine tumors. Those in the gastrointestinal tract are diagnosed in surgical specimens, clinically, and using imaging techniques (endoscopy, echoendoscopy, CT, Octreoscan, etc.). The goal of this retrospective study was to review a personal series of gastrointestinal carcinoid tumors, and to compare it to those in the literature. ...

CONTEXT AND OBJECTIVE Carcinoid tumors are very rare both in children and adults. About 85% of these tumors develop in the gastrointestinal tract. The objective of the present study was to describe our experience with children treated of carcinoid tumors, and investigate the frequency morphological findings and results. DESIGN AND SETTING Report on case series, at the Department of Pediatrics...