Rat Mx2 and rat Mx3 are two alpha/beta interferon-inducible cytoplasmic GTPases that differ in three residues in the amino-terminal third, which also contains the tripartite GTP-binding domain, and that differ in five residues in the carboxy-terminal quarter, which also contains a dimerization domain. While Mx2 is active against vesicular stomatitis virus (VSV), Mx3 lacks antiviral activity. We...

The assembly and maintenance of the muscle sarcomere requires a complex interplay of actin- and myosin-associated proteins. Myotilin is a thin filament-associated Z-disc protein that consists of two Ig-domains flanked by a unique serine-rich amino-terminus and a short carboxy-terminal tail. It binds to alpha-actinin and filamin c and is mutated in limb girdle muscular dystrophy 1A (LGMD1A). Her...

The ERM proteins--ezrin, radixin, and moesin--occur in particular cortical cytoskeletal structures. Several lines of evidence suggest that they interact with both cytoskeletal elements and plasma membrane components. Here we described the properties of full-length and truncated radixin polypeptides expressed in transfected cells. In stable transfectants, exogenous full-length radixin behaves mu...

F(1)-ATPase is an ATP-driven rotary molecular motor in which the central gamma-subunit rotates inside the cylinder made of alpha(3)beta(3) subunits. The amino and carboxy termini of the gamma-subunit form the axle, an alpha-helical coiled coil that deeply penetrates the stator cylinder. We previously truncated the axle step by step, starting with the longer carboxy terminus and then cutting bot...

Faro 61 rice starch is a Nigerian variety that has been underutilized due to low edible qualities. Consequently, the chemical modification process of carboxy methylation was contemplated for improvement physicochemical and morphological properties, as native shown be integrally unsuitable industrial applications. In this study properties modified FARO were analyzed using standard methods. Scan ...

In order to synthesize new reactive monomers obtain heat-resistant polymers and epoxyimide resins, 2-hydroxypropyl-1,3-bis-hydroxyethylester-sulphoimide 2-hydroxypropyl-1,3-bis-carboxy-me¬thylester-sulphoimide of saccharin-6-carboxylic acid were synthesized. Monomers synthesized based on 2-hydroxypropyl-1,3-bis-ester-sulphoimide acid. The resulting products characterized by elemental analysis I...

Nitronyl nitroxides, such as derivatives of 2-phenyl4,4,5,5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIOs), react with NO to form the corresponding imino nitroxides (PTIs) and NO2. PTIOs are considered as monitors of NO, stoichiometric sources of NO2, biochemical and physiological effectors, specific tools for the elimination of NO, and potential therapeutic agents. However, a better understand...