BACKGROUND The precise role of capsule endoscopy in the diagnostic algorithm of obscure gastrointestinal bleeding has yet to be determined. Despite the higher diagnostic yield of capsule endoscopy, the actual impact on clinical outcome remains poorly defined. The aim of this study was to evaluate the follow-up results of patients with obscure gastrointestinal bleeding to determine which managem...

Video capsule endoscopy (VCE) provides a noninvasive way to examine the intestinal lumen as the capsule moves along the gastrointestinal (GI) tract. However, this technology is unable to localize itself when an abnormality is found by the video source. Knowing how the capsule moves will greatly enhance the accuracy in localizing the capsule. In this paper, we develope a novel image processing t...

AIM To examine the histology of preserved anterior lens capsule in vitrectomised and lensectomised rabbit eyes with and without silicone oil tamponade. METHODS Forty adult Japanese albino rabbits received two port vitrectomy and lensectomy with or without silicone oil tamponade in one eye under both general and topical anaesthesia. Anterior lens capsule was preserved during operation. After h...

Two-dimensional capsule-substrate adhesion under an imposed Stokes flow field is numerically simulated by using the immersed interface method (IIM) with the same viscosity for the fluid enclosed by the membrane and the surrounding fluid. The capsule membrane is considered to be either impermeable or permeable while the capsule membrane is assumed to be Neo-Hookean. The interaction between the c...

This Part I paper describes the qualification of a new high performance hypromellose (hydroxypropyl methylcellulose, HPMC) capsule shell which contains no gelling agent and is dissolution friendly. The development history and the test results for a series of quality attributes including scanning electron microscopy, hygroscopicity, machineability, weight variation, powder leakage, mechanical st...

The diffusion capsule consists of a cylindrical container that can be completely filled with a solution and sealed with a small semi-permeable membrane at one end. In use, the capsule is immersed in an agitated liquid. Experiments on concentrated solutions in the capsule showed that, contrary to diffusion theory, the rate of diffusion of solute (sugars or amino acids) out of the capsule remaine...

1 One of the significant challenges in Capsule Endoscopy (CE) is to precisely determine the pathologies 2 location. The localization process is primarily estimated using the received signal strength from sensors in 3 the capsule system through its movement in the gastrointestinal (GI) tract. Consequently, the wireless 4 capsule endoscope (WCE) system requires improvement to handle the lack of t...

Kingella kingae is an encapsulated gram-negative organism that is a common cause of osteoarticular infections in young children. In earlier work, we identified a glycosyltransferase gene called csaA that is necessary for synthesis of the [3)-β-GalpNAc-(1→5)-β-Kdop-(2→] polysaccharide capsule (type a) in K. kingae strain 269-492. In the current study, we analyzed a large collection of invasive a...