Objective — to study endothelial alterations at the level of microcirculatory section blood circulation system in patients with diabetes mellitus by using capillaroscopy comprehensive examination.
 Materials and methods. The clinical examination was performed involvement 37 type 1 2 mellitus, aged 21 65 years, various manifestations severity disease. have been assigned into two groups. fir...

Blood vascular beds of the rat pituitary intermediate lobes were reproduced by injection of low viscosity methacrylate media, and then observed with a scanning electron microscope. Although the intermediate lobes of newborn and pubescent rat were poorly vascularized, the adult rat intermediate lobe contained numerous capillaries forming a fairly independent network whose density, however, was n...

The permeability of blood capillaries associated with small granule-containing (SGC) cells in rat superior cervical ganglia was investigated at ultrastructural level by employing ionic lanthanum as an electron dense tracer. In rat superior cervical ganglia, the majority of blood capillaries were nonfenestrated. Both fenestrated and nonfenestrated capillaries were observed in the area associated...

Chronic hypoxia likely plays a pivotal role in chronic renal disease, but the specifics of its involvement remain unclear. To elucidate how chronic hypoxia occurs and whether hypoxia participates in the progression of renal disease, the authors established an irreversible glomerulonephritis model induced by uninephrectomy and repeated anti-Thy-1 antibody injections. Glomerulosclerosis with micr...

Capillaries recruit when pulmonary arterial pressure rises. The duration of increased pressure imposed in such experiments is usually on the order of minutes, although recent work shows that the recruitment response can occur in <4 s. In the present study, we investigate whether the brief pressure rise during cardiac systole can also cause recruitment and whether the recruitment is maintained d...