OBJECTIVE To define an entity of abnormal vaginal flora: aerobic vaginitis. DESIGN Observational study. SETTING University Hospital Gasthuisberg, Leuven, Belgium. SAMPLE 631 women attending for routine prenatal care or attending vaginitis clinic. METHODS Samples were taken for fresh wet mount microscopy of vaginal fluid, vaginal cultures and measurement of lactate, succinate and cytokin...

The clinical symptoms of vulvovaginal candidiasis (VVC) are nonspecific, and misdiagnosis is common, leading to a delay in the initiation of antifungal treatment. We evaluated a new immunochromatography test (ICT), the CandiVagi assay (SR2B, Avrille, France), for the rapid diagnosis of VVC. This test, which employs an immunoglobulin M antibody directed against the beta-1,2-mannopyranosyl epitop...

OBJECTIVE The purpose of this study was to review the treatment outcome and safety of topical therapy with boric acid and flucytosine in women with Candida glabrata vaginitis. STUDY DESIGN This was a retrospective review of case records of 141 women with positive vaginal cultures of C glabrata at two sites, Wayne State University School of Medicine and Ben Gurion University. RESULTS The bor...

Despite acute inflammation by polymorphonuclear neutrophils (PMNs) during vulvovaginal candidiasis (VVC), clearance of Candida fails to occur. The purpose of this study was to uncover the mechanism of vaginal PMN dysfunction. Designs included assessing PMN migration, proinflammatory mediators, and tissue damage (by analysis of the activity of lactate dehydrogenase [LDH]) in mice susceptible (C3...

Objective: Our laboratory previously demonstrated that asymptomatic vaginal colonization during pregnancy is a factor predisposing patients to subsequentsymptomatic vulvovaginal candidiasis. It is unknownwhether symptoms result from strain replacement or a change in host relationship to the original colonizing strain. This study was undertaken to determine whether Candida albicans isolates from...

In 1990, more than 13 million American women received prescriptions for treating vaginitis-the most common reason for visiting the gynecologist. (1) Vaginitis caused by yeast species accounts for approximately 40% of these cases, second only to bacterial vaginosis (45%). (2,3) The incidence of vulvovaginal candidiasis (VVC) has increased dramatically in the past decade. In the United Kingdom, t...

A 75% of women will have at last one episode of vaginitis, which can become persistent in more than a half of them. Its symptoms are disturbing and carry a psychological charge for patients. Although it is frequently caused by bacterial vaginosis, vaginal candidiasis or trichomoniasis, there is other aetiology that must be taken into account, as noninfectious vaginitis and atrophic vaginitis. D...

Haematologica vol. 85(3):March 2000 4. Carlotti A, Chaib F, Couble A, Bourgeois N, Blanchard V, Villard J. Rapid identification and fingerprinting of Candida krusei by PCR-based amplification of the species-specific repetitive polymorphic sequence CKRS-1. J Clin Microbiol 1997; 35:1337-43. 5. Vazquez JA, Beckley A, Donabedian S, Sobel JD, Zervos MJ. Comparison of restriction enzyme analysis ver...

There are many reports about antifungal and antimicrobial effects of Myrtle extract. In respect to resistance of fungal strains to current antifungal drugs such as imidazole derivatives, a comparative study was carried out to Investigate the antifungal effect of Myrtle extract versus clotrimazole on candida albicans, the most common cause of vaginal candidiasis . The vaginal discharge of 500 pa...