Rapid in situ determination of surgical resection margins during breast cancer surgery would reduce patient time under anesthesia. We present preliminary data supporting the use of a fluorescent glucose analog (2-NBDG) as an optical contrast agent to differentiate freshly excised breast tissue containing cancerous cells from normal breast tissue. Multi-spectral images of 14 breast cancer specim...

Thermal death of cancerous cells may be induced by radiating single-walled carbon nanotubes (SWNTs) selectively attached via functionalization to the targeted cells. A distribution of SWNTs inside cancerous cells, on their surface, or in the inter-cellular fluid may occur during this treatment process. This work applies a random walk algorithm to calculate the effective thermal conductivity of ...

Cardiovascular diseases and cancers are the leading causes of morbidity and mortality in the world. MicroRNAs (miRNAs) are short non-coding RNAs that primarily repress target mRNAs. Here, miR-24, miR-125b, miR-195, and miR-214 were selected as representative cardio-miRs that are upregulated in human heart failure. To bridge the gap between miRNA studies in cardiology and oncology, the targets a...

This paper presents a 2-D model to calculate the electric current densities and the biopotential differences generated due to a breast cancerous cell during the hyperpolarization of the G1/synthesis (G1/S) transition. The proposed model is based on semiconductor diffusion-drift analysis, and aims to understand the biophysics associated with growing breast cancerous cells. The effect of the dura...

background: recently, the development of new biomarkers as prognostic and predictive markers in prostate cancer has been crucial. objectives: this study was aimed to determine whether serum vascular endothelial growth factor (vegf) levels would be a prognostic marker or risk assessment factor in patients with prostate cancer and to investigate whether it could differentiate cancerous tissue fro...

Recently, image mining has opened new bottlenecks in the field of biomedical discoveries and machine leaning techniques have brought significant revolution in medical diagnosis. Especially, classification problem of human cancerous tissues would assume to be one of the really challenging problems since it requires very high optimized algorithms to select the appropriate features from histopatho...