Abstract Cancer progression and the onset of therapeutic resistance are often results uncontrolled activation survival kinases. The proviral integration for Moloney murine leukemia virus (PIM) kinases oncogenic serine/threonine that regulate tumorigenesis by phosphorylating a wide range substrates control cellular metabolism, proliferation, survival. Because their broad impact on processes faci...

Cancer is a mutagenic disorder which causes uncontrollable growth of cells in the body. This uncontrolled further produces tumor. action stimulates immune system can prevent or promote tumor growth. Novel strategies for treatment cancer are also to target this system. Many conventional treatments restricted particular organ So, these therapies no more use. second most fatal worldwide. Therefore...