background: in recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. in this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...

BACKGROUND Recent studies have proposed a new prognostic factor (metastatic lymph node ratio, or MLNR) for patients with esophageal cancer (EC). However, to the best of our knowledge, there have been no studies conducted to date regarding MLNR in elderly patients. The aim of this study was to determine the prognostic value of MLNR staging compared with the 2010 American Joint Committee on Cance...

PURPOSE To determine frequency of routine radiological staging of breast cancer patients diagnosed in a German Breast Cancer Screening Center from 2007 to 2014, the incidence and consequences of distant metastases detected and the resulting implications for clinical routine. METHODS Records of 896 patients with primary breast cancer diagnosed in the Screening Centre and treated in five partic...

Tumor diameter or T stage does not reflect the actual tumor burden and is not able to estimate accurate prognosis of gastric cancer. The current study aimed to evaluate the prognostic value of tumor volume (V) for gastric cancer. A total of 3409 enrolled gastric cancer patients were randomly divided into training set (n = 1705) and validation set (n = 1704). Tumor volume was calculated by the f...

Lung cancer is one of the leading cancers for both genders all over the world. It is the most common cause of cancer death and almost reaches 20% of the total. The incidence of lung cancer has significantly increased from the early 19th century. In this manuscript we have discussed various data mining techniques that have been utilised for cancer diagnosis. The lung cancer pathologic staging is...

OBJECTIVES Preoperative evaluation of patients with suspected or confirmed lung cancer consists of clinical and radiological staging. Malignant pleural effusion is a poor prognosticator in non-small-cell lung cancer. Pleural ultrasound (PU) allows for the assessment of pleural effusion, providing real-time guidance for its aspiration and cytological analysis. Pleural Ultrasonography in Lung Can...

Objective: To investigate diagnostic value and clinical significance of ultrasonic contrast and endoscopic ultrasonography in preoperative staging of gastric carcinoma. Methods: 65 patients with gastric cancer were randomly selected from our hospital from February 2015 to February 2017 as the study objects and all of them were treated with ultrasonic contrast and endoscopic ultrasonography foll...

BACKGROUND The accuracy of endoscopic ultrasonography (EUS) for preoperative staging of gastric cancer varies. The aim of this study was to investigate the accuracy of EUS tumor (T) and node (N) staging, and to identify the histopathological factors influencing accuracy based on the detailed tumor depth of gastric cancer. METHODS In total, 309 patients with gastric cancer with confirmed patho...

Introduction: Multiple myeloma is a heterogeneous disease with different survival times among patients. Accurate prediction of prognosis in multiple myeloma is essential, as patients with a shorter survival time may require early bone marrow transplantation (BMT) and more advanced chemotherapy as a part of their first-line treatment. In the present study, a parameter, depicted by ga...

OBJECTIVE Determine diagnostic accuracy of evaluation for mediastinal invasion of esophageal cancer by multidetector computed tomography (MDCT) as compared with post-operative histopathology staging. MATERIAL AND METHOD The present study retrospectively analyzed the 64-slice MDCT of twenty-one patient's diagnosis with esophageal cancer who received surgical treatment in Siriraj Hospital. Pati...