Drug Free Tumor Theranostics In article number 2205165, Tymish Y. Ohulchanskyy and co-authors introduce hemoglobin nanocrystals for drug free, synergistic selective theranostics of colon cancer. After intravenous (i.v.) injection, these target tumor react with tumor-specific H2S H2O to enable magnetic resonance imaging guided photothermal therapy produce •OH chemodynamic therapy.

for centuries, aloe vera has been used by many different cultures. the ancient greeks, the romans, the babylonians, indians and the chinese have all used aloe vera as a medicinal plant. one of the common experimental cancer models is sarcoma-180. when aloe was administered to mice bearing s-180 tumors, the tumor growth was inhibited. aloe vera is a dietary supplement and not a regulated drug. t...

to evaluate off-label and off-nccn guidelines uses of antineoplastic drugs in a major chinese hospital.totally 1122 patients were selected from july to december 2011. then, the off-label and off-nccn guidelines uses of antineoplastic drugs were analyzed.in 798 of 1122 patients (71.12%), drugs were used for off-label. in 317 of 1122 patients (28.25%), the drugs were prescribed for off-label and ...

Based on statistics from the National Cancer Institute in US, rate of new cases cancer is 442.4 per 100,000 men and women year, more than one-third do not survive disease. diagnosis treatment are most important challenges modern medicine. The majority diagnosed at an early stage. However, possibility simultaneous application therapy (theranostics) will allow for acceleration effectiveness treat...

background: in recent years, neoadjuvant chemoradiation and subsequent surgical resection with total mesorectal excision has been shown to increase local control with decreased toxicity. neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer. in this study we evaluated the efficacy a cox-2 inhibitor on pathologic response, sphincter preservation and acute tox...

Drug Delivery In article number 2207787, Can Yang Zhang, Wei Tao, and co-workers review the recent advances in living-leukocyte-mediated drug delivery. Due to targeted response inflammatory environment, leukocytes (e.g., neutrophils, macrophages, lymphocytes) have great potential as carriers for delivery are expected bring breakthroughs precise treatment of cancer inflammation-related diseases.