background: attempts for early detection of gastric cancer have recently focused on host's genetic susceptibility factors and gene-environment interactions. we have, herein, studied the association of mthfr c677t single nucleotide polymorphism (snp) and its interaction with helicobacter pylori infection, smoking, age and gender on the risk of gastric cancer among an iranian population. met...

to determine the effectiveness of chemotherapy in the treatment of gastric cancer, a sample of 54 patients suffering from advanced adenocarcinomas were studied. the results of the study showed that the disease is more prevalent in the age group of56-60 years. the three major signs of this kind of cancer were almost equally present among both sexes in our patients. after chemotherapy, 74% of the...

background: pharmacogenomics is the study of genetic variations among individuals to predict the probability that a patient will respond to single or multidrug chemotherapy. breast cancer is one of the most common cancers among women worldwide. treatment of breast cancer by application of biological rationales gives us the ability to match the correct pharmacology to individual tumour genetic p...

background: cancer is considered among the second largest groups of noncommunicable diseases and the third cause of death in iran. ranking in the top ten cancers in the world, esophagus cancer comes out on the sixth place. this study examines the epidemiology of esophagus cancer in fars cancer registry. methods: this was a descriptive-analytic study of cases of esophagus cancer registered in fa...

Introduction: Lymphoscintigraphy is imaging of the lymphatic system and has been integrated into the sentinel node mapping procedures. Lymphoscintigraphy usually encompasses early or delayed static images. However, immediate dynamic imaging of the lymphatic basins and tumors has also been used as an adjunct lymphoscintigraphy imaging. The aim of this study was ...

Mammography remians the procedure of choice in screening asymptomatic women for breast cancer. However, in patients with symptoms, other types of imaging play an important role in the detection of malignancies. The high cost and lack of availability of PET and MRI largely precludes the use in this patient population. TI-201 is nbt the imaging agent of choice because of its wash-out and redistri...

The current study is focused on determining the mRNA expression levels of tetranectin, to detect oral squamous cell carcinoma (OSCC) and thus aiding in its classification at an early stage. RNA was isolated and cDNA synthesis was performed from the saliva samples of the patients and healthy individuals. A semiquantitative PCR based analysis was performed prior to quantitative and expression bas...