Ultrasonic measuring technique is widely using for diagnosis of osteoporosis because of its safety. A precise simulation, however, is not reported, because the behavior of ultrasonic pulse propagated in a human bone is very complicated. In this paper, ultrasonic pulse propagation in bone phantom is analyzed using elastic Finite Difference Time Domain (FDTD) method. This proposed method treats n...

PURPOSE To compare the radiographic and clinical results of medial open wedge high tibial osteotomy (OWHTO) using autogenous bone graft and allogenous cancellous bone graft for medial compartment osteoarthritis of the knee with two-year follow-up. MATERIALS AND METHODS Fifty-one patients (52 knees) who underwent medial OWHTO from October 2007 to April. 2010 were included in the study. The pat...

Background: Fluoride (F&minus) is a trace element that is incorporated into bone mineral during bone formation. This study assessed the effect of increasing Fluoride doses on the bone formation and microarchitecture on the Femur of rats by histological, and histometrical methods. Materials and Methods: A total of 16 rats was divided into one group of control and three groups of animals that re...

Transforming and insulin-like growth factors are important in regulating bone mass. Thus, one would anticipate correlations between matrix concentrations of growth factors and functional properties of bone. We therefore investigated the relationships of (1) TGF-beta2 and (2) IGF-I matrix concentrations with the trabecular microstructure, stress distribution, and mechanical properties of tibial ...

In this study, the difference in expression of human beta-defensin-3 in periprosthetic tissue and cancellous bone was observed in the periprosthetic tissue and cancellous bone of patients in the periprosthetic joint infection group, the aseptic loosening group, and the spacer treatment group as well as the synovial membrane and ilium of the normal control group. Hematoxylin and eosin staining o...

This study aimed to investigate degradation of the articular cartilage and loss of the cancellous bone in an ovariectomized (OVX) rat model simulating early human menopausal stage. Fourteen health female Sprague-Dawley rats were randomly divided into two groups (n = 7 per group): an OVX group that underwent bilateral ovariectomy to create an OVX model with low estrogen levels and a sham group i...

OBJECTIVE To determine whether fractal signature analysis (FSA) of digitised macroradiographs of knees quantifies alterations in trabecular structure in the tibial cancellous bone of osteoarthritic patients with either early or definite joint space narrowing compared with non-arthritic subjects. METHODS 90 osteoarthritic knees had macroradiographs at x5 magnification. Joint space width and FS...