Metabolic parameters were determined in fasting blood serum, fasting first morning urine, and 24-hour urine of male patients with recurrent calcium oxalate stones (N = 26, age 39.1 +/- 6.2 years) as well as in male healthy controls (N = 18, age 35.0 +/- 7.1 years), recruited from the eastern part of Croatia. The 24-hour urinary calcium excretion was significantly higher (p < 0.01) for patients ...

INTRODUCTION The choice of ideal treatment for a given lithiasis is a crucial factor for its success, minimizing the number of interventions and complications. Previous determination of stone composition and its fragility is desirable, to predict its behavior during extracorporeal shock wave lithotripsy and for evaluation of its appropriateness, or to set the indication for other techniques. ...

PURPOSE Proteins constitute a major portion of the organic matrix of human calcium oxalate (CaOx) renal stones and the matrix is considered to be important in stone formation and growth. The present study evaluates the effect of these proteins on oxalate injured renal epithelial cells accompanied by a 2D map of these proteins. MATERIALS AND METHODS Proteins were isolated from the matrix of ki...

Urolithiasis, the formation of calculi in urinary tract, has been a major problem for mankind since ages. Although the surgical techniques such as Extracorporeal Shock Wave Lithotripsy (ESWL) and Percutaneous Nephrolithotomy (PN) revolutionized the management of urolithiasis yet these approaches have some limitations. So, it is worthwhile to look for an alternative management of urolithiasis, h...

Calcium oxalate and silica minerals are common components of a variety of plant leaves. These minerals are found at different locations within the leaf, and there is little conclusive evidence about the functions they perform. Here tools are used from the fields of biology, optics, and imaging to investigate the distributions of calcium oxalate, silica minerals, and chloroplasts in okra leaves,...

Purpose: To investigate the anti-urolithiatic activity of the aqueous and alcoholic extracts of Melia azedarach Linn leaves in calcium oxalate urolithiasis in male albino rats. Methods: The effect of oral administration of aqueous and ethanol extracts of Melia azedarach Linn leaves on calcium oxalate urolithiasis has been investigated. Lithiasis was induced by oral adminstration of ethylene gly...

Calcium oxalate kidney stones are a common condition affecting many people in the United States. The concentration of oxalate in urine is a major risk factor for stone formation. There is evidence that glyoxal metabolism may be an important contributor to urinary oxalate excretion. Endogenous sources of glyoxal include the catabolism of carbohydrates, proteins, and fats. Here, we review all the...

OVEL METHODS for routine deterniiiiatiou of calcium in serum have widely replaced cumbersome “classic” methods. Further evaluation of the applicatioii of such methods to urine is needed. In our laboratory, urinary calcium has been measured by the accurate, but tedious, ClarkCollip procedure of precipitating calcium as the oxalate and titrating the oxalate with standardized peimangaiiate. Over t...

PURPOSE Calcium oxalate urolithiasis is one of the most common urinary tract diseases and is of high prevalence. The present study proposes to evaluate the antilithiatic property of hydrogen sulfide and its metabolites like thiosulfate & sulfate in an in vitro model. MATERIALS AND METHODS The antilithiatic activity of sodium hydrogen sulfide (NaSH), sodium thiosulfate (Na(2)S(2)O(3)) and sodi...

Dietary calcium lowers the risk of nephrolithiasis due to a decreased absorption of dietary oxalate that is bound by intestinal calcium. The aim of the present study was to evaluate oxaluria in normocalciuric and hypercalciuric lithiasic patients under different calcium intake. Fifty patients (26 females and 24 males, 41 +/- 10 years old), whose 4-day dietary records revealed a regular low calc...