نتایج جستجو برای: calcium current

تعداد نتایج: 933085  

Journal: :Journal of medical and dental sciences 2014
Tomoko Ebisawa Atsushi Nakajima Haruka Haida Ryo Wakita Shizuka Ando Tomohiko Yoshioka Toshiyuki Ikoma Junzo Tanaka Haruhisa Fukayama

Iontophoresis (IOP) is a noninvasive method of delivering medication transcutaneously through the skin. The electrodes used in this method should tightly fit to rough and irregular surfaces and be biologically safe, easy to handle and prepare, and cost-effective. To satisfy these requirements, calcium alginate gel can be a candidate electrode for IOP. Using calcium alginate gel electrodes, we e...

Journal: :Circulation research 1986
B P Bean M Sturek A Puga K Hermsmeyer

The patch clamp technique was used to make whole-cell recordings of calcium channel currents from single muscle cells freshly isolated from rat mesenteric arteries. The cells were found to contain two types of calcium channels; one type is activated by small depolarizations and inactivates quickly, whereas the other requires stronger depolarizations for activation and inactivates more slowly. N...

Journal: :Proceedings of the Royal Society of London. Series B, Biological sciences 1984
K S Lee D Noble E Lee A J Spindler

A small and very slow inward calcium current has been identified in isolated single ventricular cells using TTX and Cd2+ to block the sodium and fast calcium currents. Activation requires about 300 ms at the threshold potential of -60 mV, decreasing to 80 ms at the peak current voltage of -30 mV. Inactivation is five to ten times longer. Half steady-state activation and inactivation are at -50 ...

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