We present the case of a 36 year old woman with systemic lupus erythematosus with hematological, skin and joint affection, with an onset 21 years prior. The immunologic study showed positive ANA (titer 1:1,000, homogeneous pattern), anti-DNA, anti-ENA and anti-Ro (SSA). She presented multiple hard subcutaneous nodules on the trunk and extremities since 10 years prior, which tended to conglomera...

520 Ann Dermatol Received June 7, 2012, Revised December 16, 2012, Accepted for publication January 13, 2013 Corresponding author: Min Sung Kim, Department of Dermatology, Chosun University Hospital, Chosun University School of Medicine, 365 Pilmundaero, Dong-gu, Gwangju 501-717, Korea. Tel: 82-62-220-3130, Fax: 82-62-222-3215, E-mail: [email protected] This is an Open Access article dist...

Milia-like idiopathic calcinosis cutis (MICC) is characterized by smooth, firm, whitish papules resembling milia. Histologically, it appears as a well-defined, round, basophilic nodule within the upper dermis. Although the etiology and treatment remain unclear, it may resolve spontaneously. Some cases have been associated with Down syndrome, and the mean age of MICC patients was 9.9 years old. ...

INTRODUCTION CREST (calcinosis, Raynaud phenomenon, oesophageal dysmotility, sclerodactyly, and telangiectasia) syndrome comprising calcinosis cutis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia and primary sclerosing cholangitis are both chronic fibrotic diseases but the association between them is extremely rare. While primary sclerosing cholangitis has been as...