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Cancer-associated fibroblasts (CAF) remain a poorly characterized, heterogeneous cell population. Here we characterized two previously described tumor-promoting CAF sub-types, smooth muscle actin (SMA)-positive myofibroblasts and senescent fibroblasts, identifying a novel link between the two. Analysis of CAF cultured ex vivo, showed that senescent CAF are predominantly SMA-positive; this was c...
Based on the ratios of (-)-epigallocatechin-3-gallate (EGCG) and caffeine (CAF) levels found in commercial tea drinks, EGCG and CAF were co-administered to human volunteers at various EGCG/CAF ratios, and plasma EGCG was determined by high performance liquid chromatography with chemiluminescence detection. As for the results, in plasma taken after ingestion of a beverage containing 95 mg of EGC...
BACKGROUND Atrial fibrillation is a progressive disease, which in the paroxysmal form (PAF) becomes more frequent and finally becomes chronic (CAF). A retrospective analysis of patients with PAF was conducted to examine the hypothesis that angiotensin-converting enzyme inhibitors (ACEI) will prevent the progression to CAF. METHODS AND RESULTS On the basis of their treatment, 95 patients with ...
The F-box protein family is characterized by an F-box motif that has been shown to play an important role in regulating various developmental processes and stress responses. In this study, a novel F-box-containing gene was isolated from leaves of pepper cultivar P70 (Capsicum annuum L.) and designated CaF-box. The full-length cDNA is 2088 bp and contains an open reading frame of 1914 bp encodin...
A solvent extraction route is proposed to synthesize CaF(2) hollow spheres, which are formed by reversed micelles in a solvent extraction system templating the self-assembly of CaF(2) nanoparticles.
Introduction: Osteosarcopenic obesity results from multiple muscle and bone degradation and increase in fat tissue. The purpose of this study was to investigate the effect of 12 weeks elastic-band resistance training on muscle quality and serum CAF in elderly women with osteosarcopenic obesity. Method: In this randomized, single blind randomized clinical trial, 48 elderly women with osteosarcop...
Background: Several scoring systems are available to evaluate the cardiac surgery risk. Frailty increases the risk of adverse outcomes after surgery. The Frailty evaluation system is a relatively new method, and in this study, we compared the frailty scoring method with the conventional Euroscore method. Methods: This cross-sectional study was performed on 88 elderly patients (over 65 years of...
Drawing on Robinson’s cognition hypothesis, the study attempted to examine how task conditions influence EFL learners’ oral performance and whether learners’ individual differences in terms of tolerance of ambiguity and self-efficacy mediate the effects of such conditions. To this end, 62 Iranian intermediate EFL learners from private language institutes in Tehran performed four dyadic decision...
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