Objectives: Glutathione S-transferase (GST) polymorphism may play a role in the etiology of type 1 diabetes, as GST is involved to detoxification reactive oxygen radicals and synthesis proinflammatory mediators. Genetic polymorphisms renin-angiotensin aldosterone system, including angiotensin converting enzyme (ACE) gene insertion-deletion (I/D) polymorphism, can affect progression diabetes dia...

African Americans are a critical population in which to study the impact of physiologically important candidate gene mutations on the occurrence of hypertension. African Americans not only have a higher prevalence of hypertension, but the disease strikes earlier, with greater severity, and often results in death at an earlier age compared with whites in the United States. In this study, 3 physi...

The G-protein beta subunit 3 (GNB3) gene has been implicated in obesity risk; however, the molecular mechanism of GNB3-related disease is unknown. GNB3 duplication is responsible for a syndromic form of childhood obesity, and an activating DNA sequence variant (C825T) in GNB3 is also associated with obesity. To test the hypothesis that GNB3 overexpression causes obesity, we created bacterial ar...

This article refers to:Induced Polymorphism of Smectic Phases in Binary Mixture Non-Mesogenic Compounds

The angiotensin-converting enzyme (ACE) gene consists of 26 exons, it is located on chromosome 17 and its polymorphism a major contributing factor to hypertension. aim compare the efficacy Chlorthalidone Azilsartan in newly diagnosed hypertension patients association with ACE polymorphism. study was conducted department pharmacology, Rama medical college, Kanpur. After doing genetic test basic ...

Identification of Polymorphism Melanocortin 4 Receptor Gene and its Association with Egg Production Traits in Turkey

The purpose of the work – to analyze data from world literature regarding thedetermination probable role progesterone receptor gene polymorphism asa factor in occurrence premature birth.Conclusions. 1. Progesterone plays a significant inthe mechanisms development and course miscarriage, negative pregnancy outcomeand low birth weight newborns. 2. probability threat birthin different periods gest...

  Purpose: Estrogen as a crucial hormone during pregnancy acts by two types of receptors.   Estrogen receptor alpha, expressed by estrogen receptor 1 (ESR1) gene, is more abundant and   exists in all human reproductive systems. Association of ESR1 gene polymorphism has been   shown in some reproductive fields such as spontaneous abortion, endometriosis-related infertility   and in vitro fertili...

Background: This is a case-control study to determine the relationship between endothelial nitric oxide synthase (eNOS) gene -786T/C polymorphism in women with unexplaiend recurrent abortion in comparison with healty women.Materials and Methods: 95 women with history of at least 2 unexplaiend recurrent abortion in the reproductive age range 20-35 years as patients group and 95 healty women (age...

Callipyge (CLPG) is a candidate gene with significant effect on meat quality and growth in sheep. The aim of this study was to investigate the polymorphism CLPG Akkaraman breed. In study, DNAs obtained from blood samples 50 sheep used as material. CLPG/Faq1 examined all individuals using method PCR-RFLP. Only A allele AA genotype were detected after PCR-RFLP procedure. This first which investig...