several riversides in order to investigate the actual status of C. sinensis infection among reverside inhabitants. The survey results showed an overall infection rate of 21.5%: An infection rate of 40.2% in the Nakdong River basin ranked first, 30.8% in the Yeongsan River basin second, 17.3% in the Seomjin River basin third, 15.9% in the Tamjin River basin fourth, 15.7% in the South Han River b...

Copyright © 2015 Da-wei Qin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Disease of modern civilization (DMC) such as type 2 diabetes and cardiovascular disease is caused by the pressure and tension, as well as nutrition...

Orange (C. sinensis) peel flavonoids have antibacterial, antioxidant, anticancer, anti-inflammatory, and antiviral effects. However, there is a scarcity of information in the literature about orange peels flavonoids. So, we estimated phytochemicals hydro-methanolic extract C. sinensis were separated by Column chromatography confirmed with TLC HPLC. After that evaluated antimicrobial, antioxidan...

Clonorchis sinensis is a Group-I bio-carcinogen, associated with cholangiocarcinoma (CCA). The hamster is the only experimental model of C. sinensis-mediated CCA, but we oblige another animal model. The present study intended to develop a C. sinensis (Cs) mediated CCA model using C3H/He mice, co-stimulated with N-nitrosodimethyl-amine (NDMA) and dicyclanil (DC). The mice were divided into 8 gro...

AIM A study to assess the toxic effects of gamma-hexachlorocyclohexane (γ-HCH) (lindane) and ameliorative effects of Camellia sinensis on renal system has been carried out in male Wistar rats. MATERIALS AND METHODS Four groups of rats with 18 each were maintained under standard laboratory hygienic conditions and provided feed and water ad libitum. γ-HCH was gavaged at 20 mg/kg b.wt. using oli...

BACKGROUND Both tribendimidine and mebendazole are broad-spectrum drugs for anti-intestinal nematodes. We aim to assess the efficacy and safety of tribendimidine and mebendazole in patients with co-infection of Clonorchis sinensis and other helminths. METHOD We performed a randomized open-label trial in Qiyang, People's Republic of China. Eligible participants were randomly assigned to one of...

BACKGROUND Clonorchiasis is among the most neglected tropical diseases. It is caused by ingesting raw or undercooked fish or shrimp containing the larval of Clonorchis sinensis and mainly endemic in Southeast Asia including China, Korea and Vietnam. The global estimations for population at risk and infected are 601 million and 35 million, respectively. However, it is still not listed among the ...

Presently the search for new drugs from natural resources is of growing interest to the pharmaceutical industry. Natural products have been the source of new drugs since ancient times. Plants are a good source of secondary metabolites which have been found to have beneficial properties. The present study is a review of the chemistry and pharmacology of Citrus sinensis. This review reveals the t...

Clonorchiasis is caused by infection with food-borne liver fluke, namely Clonorchis sinensis, which is also considered to be a neglected tropical disease. It is estimated that over 10 million people are infected with C. sinensis in China and, subsequently, several thousand new cholangiocarcinoma cases occur annually. On May 18, 2014, China Central Television broadcasted an episode on the habit ...