A copper-catalyzed method for the oxidation of allylic and benzylic sp(3) C-H by aqueous tert-butyl hydroperoxide (T-Hydro) in water using a recyclable fluorous ligand has been developed. The reaction procedure is tolerant to additional functional groups and the fluorous ligand could be reused with little loss of catalytic activity.

The nature of the active site and the substrate specificity of poplar type II peroxiredoxin, an enzyme which preferentially uses glutaredoxin as an electron donor, were investigated in this study. The type II peroxiredoxin is able to use phospholipid hydroperoxide nearly as efficiently as hydrogen peroxide. Two of the hyper-conserved amino acid residues in peroxiredoxins have been altered, by s...

Selenoprotein P is an extracellular protein containing presumably 10 selenocysteines that are encoded by the UGA stop codon in the open reading frame of the mRNA. The function of selenoprotein P is currently unknown, although several indirect lines of evidence suggest that selenoprotein P is a free radical scavenger. We first developed a conventional procedure to isolate selenoprotein P from hu...

We developed a direct vicinal difunctionalization of alkenes with iodine and TBHP at room temperature. This iodination and peroxidation in a one-pot synthesis produces 1-(tert-butylperoxy)-2-iodoethanes, which are inaccessible through conventional synthetic methods. This method generates multiple radical intermediates in situ and has excellent regioselectivity, a broad substrate scope and mild ...

Photobiomodulation activates the mitochondrial respiratory chain components which initiates signalling cascades that promotes cellular proliferation and cytoprotection. Human keratinocyte cell cultures were modified to induce changes in mitochondrial membrane potential so that the effect of laser irradiation could be investigated. Control conditions included normal keratinocytes and cells treat...

Abstract The epoxidation reaction of the vegetable oil derivative methyl oleate with tert-butyl hydroperoxide in presence amorphous Ti–SiO 2 catalysts prepared by different methods using various silica sources was carried out. conditions were optimized. relation between properties such as specific surface area well titanium dispersion and catalytic performance focus investigation. Based on resu...

Silver/manganese dioxide (Ag@MnO 2 ) nanorods are synthesized and characterized by scanning electron microscopy, transmission energy dispersive X-ray spectroscopy, powder diffraction, photoelectron spectroscopy. It was discovered that Ag@MnO can realize hydrogen-borrowing reactions in high yields also effective for the synthesis of tert-butyl esters from aryl cyanides hydroperoxide a short peri...

The reaction of hypochlorous acid (HOCl) with hydrogen peroxide is known to generate stoichiometric amounts of singlet molecular oxygen [O2 (1Deltag)]. This study shows that HOCl can also react with linoleic acid hydroperoxide (LAOOH), generating O2 (1Deltag) with a yield of 13 +/- 2% at physiological pH. Characteristic light emission at 1,270 nm, corresponding to O2 (1Deltag) monomolecular dec...