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abstract the present study is concerned with the syntactic deviation in hafezs poetry. poems are known to be accompanied with various linguistic deviations. these deviations may be phonological, morphological and/or syntactic. the relatively high frequency of the cases of the syntactic deviation in hafezs poems makes this rhetorical feature as a main characteristic of his poetry. this thesis, ...
هدف: هدف پژوهش حاضر مطالعه اثر تمرین هوازی و مقاومتی بر نشانگرهای بیوشیمیایی اختلال آندوتلیال در افراد مبتلا به دیابت نوع 2و ارتباط آن ها با شاخص مقاومت انسولینی بود. روش : 27نفر زن مبتلا به دیابت نوع دو به طور تصادفی در 3گروه هوازی (11 نفر با دامنه ی سنی سال=50/81±7/87 و bmi=29.68±4.83) و گروه مقاومتی (11نفر با دامنه ی سنی سال=42/87±6.23 و bmi=28/93±4/83) و گروه کنترل (5 نفر با دامنه ی سنی سال...
VCAM-1 is a cell surface molecule, which has been shown to mediate leukocyte adhesion to the endothelium and subsequent transmigration. Although VCAM-1 regulates adhesion through its interaction with VLA-4, VLA-4 does not play a role in VCAM-1-dependent diapedesis, an observation suggesting the presence of a second ligand for VCAM-1. We now report a novel interaction between VCAM-1 and secreted...
BACKGROUND Cardiovascular ischemic events may occur more frequently in hypertensive patients with activated renin-angiotensin systems. We tested the hypothesis that angiotensin II (Ang II) may contribute to atherosclerosis by increasing expression of vascular inflammatory genes such as vascular cell adhesion molecule-1 (VCAM-1). METHODS AND RESULTS Rats infused with norepinephrine or Ang II f...
Endothelial vascular cell adhesion molecule-1 (VCAM-1) is expressed in response to cytokine stimulation and plays a critical role in inflammatory reactions. Previously, we developed a novel VCAM-1 inhibitor that acts through a mechanism independent of nuclear factor-kappaB activity. It suppresses the binding activity of GATA proteins in cytokine-stimulated endothelial cells, which may be relate...
Many ligands of adhesion molecules mediate costimulation of T cell activation. The generality of this emerging concept is best determined by using model systems which exploit physiologically relevant ligands. We developed such an "antigen-specific" model system for stimulation of resting CD4+ human T cells using the following purified ligands: (a) major histocompatibility complex class II plus ...
Lymphocytes migrate from the blood across endothelial cells to reach foreign substances sequestered in peripheral lymphoid organs and inflammatory sites. To study intracellular signaling in endothelial cells during lymphocyte migration, we used murine endothelial cell lines that promote lymphocyte migration and constitutively express VCAM-1. The maximum rate of resting splenic lymphocyte migrat...
Mast cells (MCs) are central to asthma and other allergic diseases, and for responses to infection and tissue injuries. MCs arise from committed progenitors (PrMCs) that migrate from the circulation to tissues by incompletely characterized mechanisms, and differentiate in situ in perivascular connective tissues of multiple organs. PrMCs derived in vitro from human cord blood were examined for a...
this study investigated the effects of manipulating the cognitive complexity of tasks along +/- few elements and the time limits on l2 learners writing performance. to conduct the study, 60 iranian efl learners with two levels of proficiency, low and high intermediate, were selected and assigned to three groups based on the time devoted to task completion. the participants performed both a simp...
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