We report experimental measurements of the acoustic emission associated with the bursting of a gas bubble at the free surface of a non-Newtonian fluid. On account of the viscoelastic properties of the fluid, the bubble is generally elongated. The associated frequency and duration of the acoustic signal are discussed with regard to the shape of the bubble and successfully accounted for by a simp...

Rhythm generation in neuronal networks relies on synaptic interactions and pacemaker properties. Little is known about the contribution of the latter mechanisms to the integrated network activity underlying locomotion in mammals. We tested the hypothesis that the persistent sodium current (I(NaP)) is critical in generating locomotion in neonatal rodents using both slice and isolated spinal cord...

We have proposed models for the ionic basis of oscillatory bursting of respiratory pacemaker neurons in the pre-Bötzinger complex. In this paper, we investigate the frequency control and synchronization of these model neurons when coupled by excitatory amino-acid-mediated synapses and controlled by convergent synaptic inputs modeled as tonic excitation. Simulations of pairs of identical cells r...

We performed a thorough bifurcation analysis of a mathematical elliptic bursting model, using a computer-assisted reduction to equationless, one-dimensional Poincaré mappings for a voltage interval. Using the intervalmappings, wewere able to examine in detail the bifurcations that underlie the complex activity transitions between: tonic spiking and bursting, bursting and mixed-mode oscillations...

Sustained neuronal activity can be broadly classified as either tonic firing or bursting. These two major patterns of neuronal oscillations are state dependent and may coexist. The dynamics and intracellular mechanisms of transitions between tonic firing and bursting in cortical networks remain poorly understood. Here we describe a detailed two-compartment conductance-based cortical neuron mode...

The generation and synchronization of bursts are studied in intrinsically spiking neurons due to stimulation with random intracellular calcium fluctuations. It is demonstrated that sufficiently strong noise could induce qualitative change in the firing patterns of a single neuron from periodic spiking to bursting modes. The dynamical mechanism of noise-induced bursting is presented based on a g...

Bursting neurons are characterized by an alternation of active and inactive state, during the active state they exhibit train of spikes and quiescent behavior in the inactive state.When bursting neurons are coupled they can synchronize depending on the coupling strength. If the coupling strength is increased above a critical value, a transition from an asynchronous state to a partial synchroniz...

Inhibitory interneurons play crucial roles in the regulation of patterns of activity in the hippocampus, and some types are thought to be vulnerable in epilepsy. The connections between excitatory and inhibitory synapses are important for generation of bursting activity in pyramidal neurons. The present study investigates the in uences of changes in the connectivity of interneurons on the patte...

We describe a simple conductance-based model neuron that includes intraand extra-cellular ion concentration dynamics and show that this model exhibits periodic bursting. The bursting arises as the fast spiking behavior of the neuron is modulated by the slow oscillatory behavior in the ion concentration variables, and vice versa. By separating these time scales and studying the bifurcation struc...

The origin of spike adding in bursting activity is studied in a reduced model of the leech heart interneuron. We show that, as the activation kinetics of the slow potassium current are shifted towards depolarized membrane potential values, the bursting phase accommodates incrementally more spikes into the train. This phenomenon is attested to be caused by the homoclinic bifurcations of a saddle...