Background The continuous use of biologic agents in the treatment of psoriasis has been reported to result in successful and sustained therapeutic effects and safety. However, some patients choose intermittent and repetitive treatment. Objective To determine the factors for selecting intermittent and repetitive ustekinumab treatment for the management of psoriasis. Methods From January 2011...

The Canadian Medical Association’s Healthcare Transformation initiative is an impressive example of the work being done to communicate the importance of the social determinants of health to the Canadian public. The communication element of this work is critical, given widely held beliefs that downplay the importance of the social determinants of health: “Despite much research indicating that hi...

Concentrations of the sum of the seven indicator PCBs (Sigma7 iPCBs) measured in non-commercial European eel (Anguilla anguilla L.) in Flanders are high: in 80% of all sampled localities, the Belgian PCB standard for fish was exceeded. The objective of this study was to assess the intake of the Sigma7 iPCBs through consumption of eel by recreational fishermen and to compare it to the intake of ...

OBJECTIVE To determine the age-weighting preferences of urban Zimbabweans in relation to health care priorities. METHOD A total of 67 randomly selected residents of a high-density area of Harare participated in the study. Participants were asked "person trade-off" questions to determine their preferences in terms of the numbers of people of various ages who would be saved from death and from ...

Background & Aims: The burden of premature mortality is used to prioritize health problems. The purpose of this study was to estimate the burden of premature mortality due to colorectal cancer in Golestan from 2011 – 2015. Materials & Methods: In this sequential cross-sectional study, based on the province mortality registration data and standard expected years of life lost (SEYLL), the burden...

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Polybrominated biphenyl (PBB), a flame-retardant material, was introduced into the food chain in Michigan in 1973 due to a manufacturing and distribution mistake. Following public concern about the long-term health effects of PBB in humans, a cohort of PBB-exposed Michigan residents was assembled in 1975. We initiated this study to determine the half-life of PBB in human sera and to understand ...