* Present address: Biological Research Lab., Tanabe Seiyaku Co ., Ltd., Osaka, Japan. Abstract-In order to clarify the neural mechanisms underlying the hyperemotion ality induced by bilateral olfactory bulb ablations in rats, changes in emotional be havior were measured after various parts of the secondary olfactory structures had been lesioned and olfactory bulb ablations had been carried out....

This work describes a biophysical model of the initial stages of vertebrate olfactory system containing structures representing the olfactory epithelium and bulb. Its main novelty is the introduction of gap junctions connecting neurons both in the epithelium and bulb, and of biologically detailed dendrodendritic synapses between granule and mitral cells in the bulb. The model was used to simula...

The expression of hepatocyte growth factor/scatter factor (HGF/SF) and its receptor, the c-met proto-oncogene product, was examined by in situ hybridization in the developing and adult murine olfactory system and compared with the expression of a known activator of HGF/SF, tissue-type plasminogen activator (tPA). In the developing olfactory canal, expression of both c-met and tPA was observed i...

The Notch signalling pathway is an important mediator of cell fate selection whose involvement in epidermal appendage formation is now becoming recognised. Hair follicle development and hair formation involve the co-ordinated differentiation of several different cell types in which Notch appears to have a role. We report intricate expression patterns for the Notch-1 receptor and three ligands, ...

Electrical stimulation of nerve fibers emerging from different positions of the olfactory epithelium was used to determine the receptive fields for 52 olfactory bulb neurons in the hamster. The responses of olfactory bulb neurons were recorded extracellularly with metal-filled micropipettes. Suprathreshold stimuli (500 microA) were applied to each of eight standard epithelial positions spaced a...

The olfactory bulb is a protruding structure formed at the rostral end of the telencephalon. Pax6-mutant mice and rats lack the olfactory bulb and, instead, develop an olfactory bulb-like structure at the lateral part of the telencephalon. Here, we report that ectopic formation of the olfactory bulb-like structure in these mutants is caused by the abnormal migration of mitral cell progenitors, ...

During olfactory development axons from the sensory epithelium migrate to the olfactory bulb and gradually establish connections with targeted glomeruli (Key and St John, 2002). The spatial distribution of these connections form the basis of a topographical mapping of odorant receptors onto the olfactory bulb (Vassar et al., 1994). The olfactory epithelium retains its capacity to undergo neurog...

Objectives: The aim of present study was to evaluate some effects of Crinum zeylanicum (C. zeylanicum) on central nervous system. Materials and Methods: C. zeylanicum methanolic bulb extract (250-1000 mg/kg orally), 2 mg chlorpromazine and 4 mg diazepam /kg body weight intraperitoneally respectively were tested in mice using Irwin test, pentobarbitone-induced sleep test, spontaneous motor acti...

to assessment alfalfa cultivars research project this research has been fulfilled in 2011 at khouzestan agricultural and natural resource research center in southwest of ahwaz in khouzestan province (iran) by position 31º20′ n, 48º40′ e. at first section for evaluation wet forage yield cultivars such as “baghdadi”, “mesasersa”, “yazdi”, “bami”, “nikshahri”, “synthetic” (main factor) and two cut...

An instantaneous rigid force model for prediction of cutting forces in ball-end milling of  sculptured surfaces is presented in this paper. A commercially available geometric engine is used to represent the cutting edge, cutter and updated part geometries. The cutter used in this work is an insert type ball-end mill. Intersecting an inclined plane with the cutter ball nose generates the cutting...