BACKGROUND Many patients do not intensify their insulin regimens. It is believed that lack of adherence may be largely due to fear of hypoglycemia. We hypothesized that utilization of an automated bolus calculator (bolus advisor) might reduce fear of hypoglycemia and encourage patients to achieve improved glycemic control. METHOD We surveyed 1,412 type 1 diabetes mellitus (T1DM) patients trea...

We examined the measurement error in inhaled and exhaled aerosol concentration resulting from the bolus delivery system when small volumes of monodisperse aerosols are inspired to different lung depths. A laser photometer that illuminated approximately 75% of the breathing path cross section recorded low inhaled bolus half-widths (42 ml) and negative deposition values for shallow bolus inhalati...

AIM To assess the diagnostic accuracy and radiation dose of split-bolus multidetector-row computed tomography (MDCT) protocol in the detection and characterization of focal liver lesions in oncologic patients. PATIENTS AND METHODS We retrospectively analyzed triphasic CT at initial diagnosis and follow-up split-bolus 64-detector row CT protocol in 48 oncologic patients with focal liver lesion...

PURPOSE To investigate the incremental diagnostic value of dual-bolus over single-contrast-bolus first pass magnetic resonance myocardial perfusion imaging (MR-MPI) for detection of significant coronary artery disease (CAD). MATERIALS AND METHODS Patients (n = 49) with suspected CAD underwent first pass adenosine stress and rest MR-MPI and invasive coronary angiography (CA). Gadolinium diethy...

We present a novel experimental approach which allows extraction of both spatial and temporal information on charge dynamics in organic solar cells. Using the wavelength dependence of the photonic structure in these devices, we monitor the change in spatial overlap between the photogenerated hole distribution and the optical probe profile as a function of time. In a model system we find evidenc...

in Monkey Lateral Intraparietal Area Neurons 6 7 8 9 Joonkoo Park and Jun Zhang 10 11 Department of Psychology 12 University of Michigan 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 Corresponding author: 30 31 Jun Zhang ([email protected]) 32 Department of Psychology, University of Michigan 33 530 Church St., Ann Arbor, Michigan 48109 34 35 36

The construction of a model of the gravitational-wave (GW) signal from generic configurations of spinning-black-hole binaries, through inspiral, merger, and ringdown, is one of the most pressing theoretical problems in the buildup to the era of GW astronomy. We present the first such model in the frequency domain, PhenomP, which captures the basic phenomenology of the seven-dimensional paramete...

The contact process is used as a simple spatial model in many disciplines, yet because of the buildup of spatial correlations, its dynamics remain difficult to capture analytically. We introduce an empirically based, approximate method of characterizing the spatial correlations with only a single adjustable parameter. This approximation allows us to recast the contact process in terms of a stoc...

BACKGROUND Complement, activated during myocardial ischemia and reperfusion, causes myocardial damage through multiple processes. The COMplement inhibition in Myocardial infarction treated with Angioplasty (COMMA) trial was performed to determine the effect of pexelizumab, a C5 complement inhibitor, on infarct size in patients with ST-segment-elevation myocardial infarction (MI) undergoing prim...

BACKGROUND The purpose of this study was to determine if persistent changes in the duration of bolus movement through the pharynx and bolus movement coordination with pharyngeal swallowing gestures occur after treatment of oropharyngeal carcinoma with chemoradiation therapy. METHODS The timing of bolus movement and coordination with swallowing gestures was evaluated in 30 patients using a mod...