Human breast cancers are known to preferentially metastasize to skeletal sites, however, the mechanisms that mediate the skeletal preference (orthotropism) of specific types of cancers remains poorly understood. There is a significant clinical correlation between the expression of bone sialoprotein (BSP) and skeletal metastasis of breast cancers. Our laboratory, as well as others, have proposed...

Implants of allogenic demineralized bone matrix were placed in distinct in vivo environments, i.e. calvarial (bony) and subcutaneous (soft tissue) sites. Detailed analyses of the biochemical components were performed. Quantitative levels of osteopontin (OPN), bone sialoprotein (BSP) and calcium phosphate (Ca-P) deposition within each implant environment varied as a function of new bone formatio...

In this paper we describe an hybrid algorithm for an even number of processors based on an algorithm for two processors and the Overlapping Partition Method for tridiagonal systems. Moreover, we compare this hybrid method with the Partition Wang’s method in a BSP computer. Finally, we compare the theoretical computation cost of both methods for a Cray T3D computer, using the cost model that BSP...

This paper addresses the dag scheduling problem, proposing the bulk synchronous parallel (BSP) model as a framework for the derivation of general purpose parallel computer schedules of uniform dags, i.e., of dags that stand for tightly-nested loops with computable distance vectors. A general technique for the BSP scheduling of normalised uniform dags is introduced and analysed in terms of the B...

The Bulk Synchronous Parallel (BSP) computational model has emerged as the dominant distributed framework to build large-scale iterative graph processing systems. While its implementations (e.g., Pregel, Giraph and Hama) achieve high scalability, frequent synchronization and communication among the workers can cause substantial parallel inefficiency. To help address this critical concern, this ...

mcz THE INThODUOTION of sulfobromophthalein (BSP) as a test for liver function, (1) it has gained wide acceptance and is considered (2) the most reliable single test for evaluating liver function. BSP extraction by the liver has also been used as a measure of hepatic blood flow. Measurement of BSP in water solution is relatively simple in that the compound is a dye, purple in alkali, and colorl...

Sperm motility is, for its relation to cell viability and fertility, a central component of the spermiogram, where consideration of motion patterns allows discrimination of sub-populations among boar spermatozoa. Extension and cryo-preservation imposes changes in these patterns in connection to handling, additives, temperature changes and the removal of boar seminal plasma (BSP) which apparentl...

Using expression cloning in Xenopus laevis oocytes, we have isolated a cDNA encoding a rat liver organic anion-transporting polypeptide (oatp). The cloned oatp mediated Na(+)-independent uptake of sulfobromophthalein (BSP) which was Cl(-)-dependent in the presence of bovine serum albumin (BSA) at low BSP concentrations (e.g., 2 microM). Addition of increasing amounts of BSA had no effects on th...

The orientation of the TATA box is thought to direct downstream transcription of eukaryotic genes by RNA polymerase II. However, the putative TATA box in the promoter of the bone sialoprotein (BSP) gene, which codes for a tissue-specific and developmentally regulated bone matrix protein, is inverted (5'-TTTATA-3') relative to the consensus TATA box sequence (5'-TATAAA-3') and is overlapped by a...

The Bulk-Synchronous Parallel (BSP) model of computation has been proposed by L.G. Valiant as a unifying and bridging model for the design, analysis and implementation of parallel algorithms that are both scalable and portable, among diverse parallel machines. In this work we present direct BSP algorithms for dense matrix computations such as matrix multiplication, LU decomposition, determinant...