A workshop on the follow-up care of high-risk infants sponsored by the National Institute of Child Health and Human Development, National Institute of Neurologic Disorders and Stroke, and the Centers for Disease Control and Prevention was held June 19-20, 2002. There are currently no standardized guidelines for provision of follow-up services for high-risk infants in tertiary care centers despi...

Background: Pompe disease is a progressive metabolic neuromuscular disorder resulting from deficiency of lysosomal acid -glucosidase (GAA). Infantile-onset Pompe disease is characterized by cardiomyopathy, respiratory and skeletal muscle weakness, and early death. The safety and efficacy of recombinant human (rh) GAA were evaluated in 18 patients with rapidly progressing infantile-onset Pompe d...

Nutrients are critical for optimal brain development and function. Although maintenance of adequate intake of all nutrients throughout life is important for brain health and function, certain nutrients have a more profound effect on brain development than others. The timing of nutrient supplementation or deprivation also has an important effect on brain development and function. Nutrient intake...